Book Reviews

Zuckerman: Scientist Extraordinary by Bernard Donovan BioScientifica, Bristol, 2005, 555pp. ISBN 1‐901978249 £24.95 Negotiating licences for digital resources by Fiona Durrant Facet Publishing, 2006, ISBN 1 85604 586 2 Metadata for Information Management and Retrieval By David Haynes Facet Publishing, 2004, ISBN 1 85604 4890     

The publishing imperative: the pervasive influence of publication metrics

This article summarizes the effects of the increasing global trend towards measuring research quality and effectiveness through, in particular, publication‐based metrics, and its effects on scholarly communication. Such metrics are increasingly influencing the behaviour patterns of administrators, publishers, librarians, and researchers. Impact and citation measures, which often rely solely on Thomson Scientific data, are examined in the context of university league tables and research assessment exercises. The need to establish alternate metrics, particularly for the social sciences and humanities, is emphasized, as is an holistic approach to scholarly communication agenda.     

One step antibody-mediated isolation and patterning of multiple cell types in microfluidic devices

Cell-cell interactions play a key role in regeneration, differentiation, and basic tissue function taking place under physiological shear forces. However, current solutions to mimic such interactions by micro-patterning cells within microfluidic devices have low resolution, high fabrication complexity, and are limited to one or two cell types. Here, we present a microfluidic platform capable of laminar patterning of any biotin-labeled peptide using streptavidin-based surface chemistry. The design permits the generation of arbitrary cell patterns from heterogeneous mixtures in microfluidic devices. We demonstrate the robust co-patterning of α-CD24, α-ASGPR-1, and α-Tie2 antibodies for rapid isolation and co-patterning of mixtures of hepatocytes and endothelial cells. In addition to one-step isolation and patterning, our design permits step-wise patterning of multiple cell types and empty spaces to create complex cellular geometries in vitro. In conclusion, we developed a microfluidic device that permits the generation of perfusable tissue-like patterns in microfluidic devices by directly injecting complex cell mixtures such as differentiated stem cells or tissue digests with minimal sample preparation.     

Open and distance learning in the Gobi Desert: Non‐formal education for nomadic women

The use of open and distance learning for non‐formal education is much less canvassed in the literature than for formal education. This paper provides a case study, grounded in practice, of the first open and distance learning for non‐formal education in Mongolia, a developing country undergoing rapid transition in the 1990s from a command to a market economy and from communism to a multi‐party democracy. The paper outlines the project and its context, explains the rationale for it, and analyses its achievements, limitations and lessons. It also identifies the additional problems for Open and Distance Education (ODE) in a context of rapid economic transition.     

The effects of isolation and handling on reactivity to footshock and tactile dorsal stimulation

The effects of isolation and handling on the reactivity of rats to two tactile stimuli were assessed in two experiments. In the first experiment, reactivity to more intense footshock was increased in rats raised in isolation but was not affected by handling by an experimenter. In the second experiment, increased reactivity to airpuff stimuli presented to the dorsal surface of isolation-reared rats was reduced by handling. The data suggest that the effects of handling on shock-motivated behaviors are not due to altered reactivity to shock and that the effect of housing or handling must be considered in behavioral tests in which reactivity to tactile stimulation might play a role as dependent or independent variables.     

Using Paper Helicopters to Teach Statistical Process Control

This hands‐on project uses a paper helicopter to teach students how to distinguish between common and special causes of variability when developing and using statistical process control charts. It allows the student to experience a process that is out‐of‐control due to imprecise or incomplete product design specifications and to discover how the process can be brought into control through the use of standardized product specifications and associated construction procedures. It also allows the student to experience common causes of variability, to distinguish these from the special causes of variability resulting from the incomplete design specifications, and to discover how standardization reduces process variability. The project has been used in both undergraduate and MBA classes and demonstrates these concepts in a way that is easy for the student to understand and remember.     

How Exemplar Counselor Advocates Develop Social Justice Interest: A Qualitative Investigation

The authors examined the experiences of 10 peer‐nominated exemplar counselor advocates using grounded theory methodology (Strauss & Corbin, 1998 ). Analysis by the authors yielded a model of how exemplar counselor advocates develop a social justice interest and provided key insights on how counselor educators can enhance social justice interest in their students. Implications for supervisors and scholars are presented.