Carnosine in health and disease

Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.     

Social‐Information‐Processing Skills of Kindergarten Children with Developmental Learning Disabilities

The study examined the social‐information‐processing skills of kindergarten children with developmental learning disabilities (LD) utilizing Crick and Dodge's (1994) model of children's social adjustment as a theoretical framework. Participants consisted of 20 kindergarten children with developmental LD who attended three integrated kindergartens and 20 children without developmental LD from the same kindergartens. Participants were assessed on social‐information‐processing skills, feelings of loneliness, sense of coherence, and teachers' ratings of behavioral problems and positive resources. The results indicated that girls with developmental LD performed significantly lower on two information‐processing steps—the response decision and the enactment steps—than did girls without LD. Such differences were not found for boys. The results also showed that the social‐information‐processing skills of children with developmental LD were correlated with teachers' ratings.     

Review article

Ducellier, A., Kaplan, M., Martin, Bernadette, avec la collaboration de Françoise Micheau. Le Moyen Âge en Orient. Byzance et l'Islam. Des Barbares aux Ottomans. Paris: Hachette Histoire Université, 1990.     

Cross-cultural argument interactions between Israeli-Jews and Palestinians

This study examined the argument patterns that result when Israeli-Jews and Palestinians confront each other during group dialogues. We tested predictions derived from two theories. The first was a theory of cultural communication which predicted that Israeli-Jews and Palestinians would argue in a manner consistent with their respective cultural communication codes known as dugri and musayra respectively. Thus, the Israeli-Jews were expected to be assertive and the Palestinians more accommodating. The second theory was rooted in majority/minority power relations and predicted the opposite. The data were generated from reconciliation-based dialogue groups of Israeli-Jews and Palestinians. Communicative acts were coded according to the Conversational Argument Coding Scheme. Analysis of covariance was used to determine which patterns of argument distinguished the groups, and to identify variance attributable to lag sequences and individuals. The results were supportive of predictions from majority/minority power relations.     

Book reviews

Association of Research Libraries     

Input-Based Approaches to Teaching Grammar： A Review of Classroom-oriented Research

INTRODUCTION There is now a substantial body of research that has investigated the role of form-focused instruction in assisting learners to learn the grammar of a second language (L2). Recent comprehensive surveys of this research have been provided by N. Ellis (1995), R. Ellis (1990; 1994; 1997), Larsen-Freeman and Long (1991), Long (1988), Spada (1997),