排序方式： 共有8条查询结果，搜索用时 15 毫秒
1
1.
2.
3.
Effect of lead exposure on the immune function of lymphocytes and erythrocytes in preschool children
INTRODUCTION Over the past few years, systematic studies onthe effect of lead exposure on the human body haveled to an understanding that lead is neurotoxic andhas adverse effect on the immune system. So far,however, research on the immunotoxic effects oflead has been limited to animal experiments andpeople with occupational exposure to lead (Shen etal., 1996; Mishra et al., 2003; Liu et al., 2000).Presently, there are no reports on the influence oflead exposure on lymphocyte and … 相似文献
4.
Objective: To study the clinical therapy and prognosis in children with transient congenital hypothyroidism (CH).Methods: Fifty-seven children with CH diagnosed after neonatal screening were treated with low-dosage levothyroxine (L-T4).Follow-up evaluation included the determination of TT3, TT4 and TSH serum levels and the assessment of thyroid gland morphology, bone age, growth development and development quotients (DQ). A full check-up was performed at age 2, when the affected children first discontinued the L-T4 treatment for 1 month, and one year later. Development quotients were compared (16.25±3.87) μg/d. Mean duration of therapy was (28.09±9.56) months. No significant difference was found between study group and control group in the DQ test (average score (106.58± 14.40) vs (102.4±8.6), P＞0.05) and 96.49% of the CH children achieved a test score above 85. Bone age, 99mTc scans and ultrasonographic findings were all normal, and evaluation of physical development was normal too, as were the serum levels of TT3, TT4 and TSH after one year of follow-up. Conclusion: A L-T4 dosage of and physical development at age 2. So it is possible for CH children to stop taking medicine if their laboratory findings and physical development are all normal after regular treatment and 2～3 years of follow-up. 相似文献
5.
6.
Effect of lead exposure on the immune function of lymphocytes and erythrocytes in preschool children
Objective: To investigate the influence of lead exposure on the immune function of lymphocytes and erythrocytes in preschool children. Materials and methods: A group of 217 children three to six years of age from a rural area were given a thorough physical examination and the concentration of lead in blood samples taken from each subject was determined. The indices of lymphocyte immunity (CD 3CD 4, CD 3CD 8, CD 4CD 8, CD-3CD 19) and erythrocyte immunity (RBC-C3b, RBC-IC, RFER, RFIR, CD35 and its average fluorescence intensity) of 40 children with blood lead levels above 0.483 μmol/L were measured and compared with a control group. Results: The blood lead levels of the 217 children ranged from 0.11 μmol/L to 2.11 μmol/L. The CD 3CD 4and CD 4CD 8 cells were lower (P＜0.01) and the CD 3CD 8 cells were higher in the lead-poisoned subjects than those in the control group (P＜0.05). CD 3 and CD-3CD 19 did not show significant differences. Although the RBC-C3b rosette forming rate was lower and the RBC-IC rosette forming rate was higher in the lead-poisoned group, this difference could not be shown to be statistically significant (P＞0.05). RFIR was found to be lower in the lead-poisoned group (P＜0.01). Compared with the control group, the positive rate of CD35 was not found to be significantly different in a group of 25 lead-poisoned children (P＞0.05), while the average fluorescence intensity was lower in the lead-poisoned group (P＜0.05). Conclusion: Lead exposure can result in impaired immune function of T lymphocytes and erythrocytes in preschool children. 相似文献
7.
很多孩子都有缺钙的现象。孩子什么时候应该补钙?怎么知道孩子是否缺钙?补钙应该补到什么时候?佝偻病是不是因为缺钙引起的?给孩子补钙是一个大问题,既然有这么多疑问,那么让我们来问问医生吧。 相似文献
8.
1