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1.
Giving parents a choice with regard to their children's education has been central to the political discourse of school reform at least since the 1988 Education Reform Act (ERA). With regard to children with a Statement of special educational needs (SSEN), a plethora of policies and laws have given parents the right not only to choose a school, but also to appeal to decisions in the best interest of their children. Yet, despite the discourse of school choice, the implementation and practice of such reforms is neither assured nor simple. Participants in this study indicated that they have little choice of suitable provision and are having to compromise either the academic or the social aspects of their child's schooling. This article argues that for many parents whose children have a Statement of SEN, the choice of a school is often a dilemma, as ‘nowhere seems to fit’. 相似文献
2.
G. N. Raval L. J. Parekh D. D. Patel F. P. Jha R. N. Sainger P. S. Patel 《Indian journal of clinical biochemistry : IJCB》2004,19(2):60-71
Sialic acid, the end moieties of the carbohydrate chains are biologically important and essential for functions of glycoconjugates
and are reported to be altered in cancer patients. Two hundred and twenty five breast cancer (BC) patients, 100 patients with
benign breast disease (BBD) and 100 healthy females (controls) were enrolled for the study. Eight hundred and twenty four
follow-up samples of 225 breast carcinoma patients were also evaluated. The association of sialic acid forms, sialyltransferase
and α-2–6 sialoproteins levels with presence and extent as well as prognosis of breast carcinoma was studied. Serum sialic
acid forms and sialyltransferase revealed significantly elevated levels among untreated breast cancer patients as compared
to the controls, patients with BBD as well as cancer patients in remission. Non-responders showed comparable levels of the
markers with those found in breast cancer patients at the time of diagnosis. Higher levels of sialic acid forms at diagnosis
were associated with poor prognosis. A positive correlation between serum levels of different forms of sialic acids and extent
of malignant disease was observed. The changes in serum proteins with terminal α-2–6 sialic acid correlated well with alterations
in the levels of sialic acid forms and sialyltransferase. Malignant tissues showed elevated levels of sialic acid and sialyltransferase
as compared to surrounding normal tissues.
The results suggested potential utility of these markers in evaluation of clinical outcome. 相似文献
3.
David R. Kaufman Vimla L. Patel Sheldon A. Magder 《International Journal of Science Education》2013,35(3):369-386
Analogical reasoning is increasingly recognized as an important instrument for promoting conceptual change in science learning. This study characterized students' and physicians' spontaneous use of analogies in reasoning about concepts related to the mechanical properties of cardiovascular physiology. The analogies were made in response to questions at different levels of abstraction from basic physiology to clinical problems. The results indicate that analogies generated by subjects facilitated explanations in a number of ways. These include creating coherent representations in novel situations, bridging gaps in understanding, and triggering associations which result in modified explanations. Subjects at different levels of expertise used analogies differently. The more expert subjects used analogies to facilitate articulation and communication; that is, to illustrate and expand on their explanations. Novices and advanced medical students used more between‐domain analogies to explain all categories of questions. This is less evident in physicians' responses to pathophysiological and clinical problems. The paper discusses ways in which analogies can be used productively, and identifies factors that can lead to a counter‐productive use of analogies resulting in misconceptions and erroneous explanations. 相似文献
4.
Adrian Furnham Mark Batey Tom W. Booth Vikita Patel Dariya Lozinskaya 《Thinking Skills and Creativity》2011,6(2):114-121
Two studies are reported that used multiple measures of creativity to investigate creativity differences and correlates in arts and science students. The first study examined Divergent Thinking fluency, Self-Rated Creativity and Creative Achievement in matched groups of Art and Science students. Arts students scored higher than Science students on two of the three measures. Regression analysis indicated that the educational domain demographic variable was the most consistent predictor of all three measures of creativity. The second study compared natural science, social science and arts students on two performance and two preference measures of creativity, whilst controlling for the effects of general intelligence. Results indicated only Self-Rated Creativity displayed significant group differences, with the regression analysis suggesting a stronger role of personality variables. The differences between the groups and implications for the measurement of creativity are considered. 相似文献
5.
Archer Louise Calabrese Barton Angela M. Dawson Emily Godec Spela Mau Ada Patel Uma 《Cultural Studies of Science Education》2022,17(2):405-438
Cultural Studies of Science Education - While there are many different frameworks seeking to identify what benefits young people might derive from participation in informal STEM (Science,... 相似文献
6.
Xinyu Lu Saurin Patel Meng Zhang Sang Woo Joo Shizhi Qian Amod Ogale Xiangchun Xuan 《Biomicrofluidics》2014,8(2)
Electrophoresis plays an important role in many applications, which, however, has so far been extensively studied in Newtonian fluids only. This work presents the first experimental investigation of particle electrophoresis in viscoelastic polyethylene oxide (PEO) solutions through a microchannel constriction under pure DC electric fields. An oscillatory particle motion is observed in the constriction region, which is distinctly different from the particle behavior in a polymer-free Newtonian fluid. This stream-wise particle oscillation continues until a sufficient number of particles form a chain to pass through the constriction completely. It is speculated that such an unexpected particle oscillating phenomenon is a consequence of the competition between electrokinetic force and viscoelastic force induced in the constriction. The electric field magnitude, particle size, and PEO concentration are all found to positively affect this viscoelasticity-related particle oscillation due to their respective influences on the two forces. 相似文献
7.
Davide Girardelli Vijay K. Patel Janine Martins-Shannon 《Educational Research and Evaluation》2017,23(3-4):119-137
An extended model based on the theory of planned behaviour (TPB) was used to study Chinese English as a foreign language (EFL) students’ in-class participation. The model included the core TPB constructs (behavioural intentions, attitudes, subjective norms, and perceived behavioural control/self-efficacy) and 2 additional constructs (foreign language classroom anxiety and face-saving) frequently discussed in the literature about Chinese EFL classroom dynamics. A total of 199 Chinese students enrolled in a Sino-American international branch campus were surveyed. The results of a partial least squares (PLS) path modelling analysis revealed that attitudes, subjective norms, perceived behavioural control/self-efficacy, and face-saving explained 46% of the variance in intentions to participate in English in class. Perceived behavioural control/self-efficacy fully mediated the negative indirect effect of foreign language classroom anxiety on intentions. Pedagogical implications and future directions are discussed for implementation purposes. 相似文献
8.
Franky D. Shah Rasheedunnisa Begum Bhairavi N. Vajaria Kinjal R. Patel Jayendra B. Patel Shilin N. Shukla Prabhudas S. Patel 《Indian journal of clinical biochemistry : IJCB》2011,26(4):326-334
Oral cancer has emerged as an alarming public health problem with increasing incidence and mortality rates all over the world.
Therefore, the implementation of newer screening and early detection approaches are of utmost importance which could reduce
the morbidity and mortality associated with this disease. Sensitive and specific biomarkers for oral cancer are likely to
be most effective for screening, diagnosis, staging and follow-up for this dreaded malignancy. Unlike other deep cancers,
oral cancer is located in oral cavity. Hence, the direct contact between saliva and oral cancer lesion makes the measurement
of tumor markers in saliva an attractive alternative to serum and tissue testing. The DNA, RNA and protein molecules derived
from the living cancer cells can be conveniently obtained from saliva. Thus, salivary biomarkers, a non-invasive alternative
to serum and tissue-based biomarkers may be an effective modality for early diagnosis, prognostication and monitoring post
therapy status. In the current post-genomic era, various technologies provide opportunities for high-throughput approaches
to genomics and proteomics; which have been used to evaluate altered expressions of gene and protein targets in saliva of
oral cancer patients. The emerging field of salivary biomarkers has great potentials to prove its clinical significance to
combat oral cancer. Hence, we have reviewed importance of several salivary genomics and proteomics biomarkers for oral cancer. 相似文献
9.
Carl Corter Sejal Patel Janette Pelletier Jane Bertrand 《Early education and development》2013,24(5):773-794
Research Findings: Integrated services for young children and families are part of the new policy landscape in early childhood, but there is limited evidence of the effectiveness of these programs and how they develop on the ground. This study examined the use of the Early Development Instrument (EDI) as both a summative program evaluation tool and as a formative program improvement tool supporting practitioners in Toronto First Duty, an integrated services demonstration project that combined kindergarten, child care, and parenting supports in public schools. Pre-post comparisons at community demonstration sites and comparisons with matched community sites using the EDI suggested that the demonstration program was associated with modest improvements in emotional and social domains of children's development. Mixed methods and multiple measures were used to contextualize summative findings in case studies across demonstration sites. The case studies explored how integration was implemented at different sites and how dimensions of enacted integration might contribute to positive outcomes for children and families. A case study of one site showed how an integrated staff team used EDI school-level profiles, along with formative feedback on program quality, to target and improve programming. Over the course of implementation, the integrated program environment quality ratings and EDI scores improved in relevant areas assessing quality of interaction and social–emotional development. Practice or Policy: Findings are discussed in terms of the role of the EDI in program evaluation and in improvement of practice. The potential value of integrated early childhood services and the challenges of evaluating complex community initiatives are also discussed. 相似文献
10.
Yogesh M. Patel Sanidhya Jain Abhishek Kumar Singh Kedar Khare Sarita Ahlawat Supreet Singh Bahga 《Biomicrofluidics》2020,14(6)
We present design, characterization, and testing of an inexpensive, sheath-flow based microfluidic device for three-dimensional (3D) hydrodynamic focusing of cells in imaging flow cytometry. In contrast to other 3D sheathing devices, our device hydrodynamically focuses the cells in a single-file near the bottom wall of the microchannel that allows imaging cells with high magnification and low working distance objectives, without the need for small device dimensions. The relatively large dimensions of the microchannels enable easy fabrication using less-precise fabrication techniques, and the simplicity of the device design avoids the need for tedious alignment of various layers. We have characterized the performance of the device with 3D numerical simulations and validated these simulations with experiments of hydrodynamic focusing of a fluorescently dyed sample fluid. The simulations show that the width and the height of the 3D focused sample stream can be controlled independently by varying the heights of main and side channels of the device, and the flow rates of sample and sheath fluids. Based on simulations, we also provide useful guidelines for choosing the device dimensions and flow rates for focusing cells of a particular size. Thereafter, we demonstrate the applicability of our device for imaging a large number of RBCs using brightfield microscopy. We also discuss the choice of the region of interest and camera frame rate so as to image each cell individually in our device. The design of our microfluidic device makes it equally applicable for imaging cells of different sizes using various other imaging techniques such as phase-contrast and fluorescence microscopy. 相似文献