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1.
Fadhaa A. Ghafil Bassim I. Mohammad Hussain S. Al-Janabi Najah R. Hadi Hayder A. Al-Aubaidy 《Indian journal of clinical biochemistry : IJCB》2021,36(1):81
Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses. 相似文献
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Children are sensitive to a number of considerations influencing distributions of resources, including equality, equity, and reciprocity. We tested whether children use a specific type of reciprocity norm—market norms—in which resources are distributed differentially based strictly on amount offered in return. In two studies, 195 children 5–10 years and 60 adults distributed stickers to friends offering same or different amounts of money. Overall, participants distributed more equally when offers were the same and more unequally when offers were different. Although sensitive to why friends offered different amounts of money, children increasingly incorporated market norms into their distributions with age, as the oldest children and adults distributed more to those offering more, irrespective of the reasons provided. 相似文献
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教练员与运动员关系的研究 总被引:7,自引:0,他引:7
我国竞技体育,教练员与运动员关系好的不乏其人,他们努力训练,通力合作,为我国的竞技体育的腾飞作出了卓越的贡献,但也有些教练员与运动员关系不融洽,使运动员过早地离开运动场,失去了为国争光的机会。文章通过教练员和运动员关系的研究,旨在为提高竞技运动水平和教练员在选材、训练时提供参考。 相似文献
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健康作为一种人力资本投资对提高生产力、促进经济发展和个人发展有着重要的作用。它可以提高劳动者的生产效率,刺激教育方面的投资,使人具有更多的时间和能力利用其他资本要素,具有更大的财力(因减少医疗费用)用于其他方面的投资。所以进行人力资本投资时,不可忽视健康这一要素,它也是人力资本形成的重要途径,也对经济增长起着有力的推动作用。 相似文献
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Nancy K. Moore Margaret T. Shaffer Rita Furst Seifert 《Contemporary educational psychology》1985,10(1):83-92
This study investigated the basic cognitive skills soldiers must possess before entering the Army, skills that are needed for successful completion of entry-level training. Judgments of 126 instructors from 25 military occupational specialties were obtained on 129 candidate skills, which resulted in the identification of 55 basic skills. Factor analysis of these 55 skill items resulted in 11 interpretable factors. Mean scores on the factors were compared across factors and across Army training schools. The results of the study suggest that, for all occupational specialties studied, skills related to the learning process are as crucial as traditional academic skills for successful training course completion. These results have important implications for training for the Army as well as for industry. 相似文献
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The purpose of this study was to describe the development of elementary students' skill in making predictions and of their understanding of what predicting means. The study involved observing and assessing the performance of 167 children on the Physical Manipulation Test (PMT), a test involving the manipulation of science materials and equipment. Children were interviewed about what they understand predicting to mean, how they use it at school and at home, and why they think it is important. For each of the seven topics tested, even the youngest children were able to offer predictions. Accuracy varied with the topic, increasing between Grades 1 and 4 and leveling off after that. The increase in skill involved children's growing ability to attend to patterns discerned through their own observations. Four levels in the development of predicting skill, as it relates to particular topics, are described. Children's understanding of predicting showed steady improvement through Grade 6. Children's awareness of their use of predicting at school and at home, and their ability to explain the importance of predicting, also increased through Grades 1 to 6, with a spurt at Grade 4. Children understood predicting to be an internal process in which one uses knowledge to anticipate a future event; they regarded predicting as an important way of being intellectually involved with the world. 相似文献