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Individual Differences in Childhood Behavior Disorders Associated With Epigenetic Modulation of the Cortisol Receptor Gene 下载免费PDF全文
Mark R. Dadds Caroline Moul David J. Hawes Antonio Mendoza Diaz John Brennan 《Child development》2015,86(5):1311-1320
Behavioral/emotional difficulties in children are the first sign of mental health problems. These problems are however, heterogeneous. A domain that may identify homogenous subgroups is hypothalamic–pituitary–adrenal function. This study tested whether epigenetic regulation of glucocorticoid receptor gene could explain the co‐occurrence of anxiety problems in children with behavior problems. Four‐ to 16‐year‐old clinically referred children (N = 241) were measured for psychiatric symptoms, methylation of target CpG sites in blood or saliva, and morning cortisol levels in those who gave blood. Increased methylation of promoter 1F CpG sites was associated with higher vulnerability to co‐occurring internalizing symptoms and morning cortisol. The results support increasing optimism that epigenetic regulation of key neuroendocrine systems might help explain hitherto unfathomable individual differences in susceptibility to psychiatric symptom profiles. 相似文献
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As Colombia began to develop its Intangible Cultural Heritage (ICH) policy, it signed an agreement with the Smithsonian Center for Folklife and Cultural Heritage to collaborate on a Smithsonian Folklife Festival of Colombia's national living traditions, to be shown on the National Mall in 2011. This essay addresses the role of the Smithsonian Folklife Center in advocating for a cultural heritage policy grounded in cultural democracy and intercultural dialogue, as well as its collaboration with UNESCO in crafting the 2003 convention for the protection of intangible cultural heritage. We focus on the Center's signature collaborative program, the Smithsonian Folklife Festival, and on our experience with the 2011 Festival program, Colombia: The Nature of Culture. We examine the relationship between the Festival and Colombia's intangible cultural heritage communities, policies, and practices, through intercultural dialogues that contribute to shaping Intangible Cultural Heritage policy from the bottom up. 相似文献
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John M. Diaz Kevin D. Stallings Birendra KC 《Educational Research and Evaluation》2013,19(5-6):466-484
Partnership evaluation typically occurs during the final stages either to assess why a collaborative effort did not work or to identify the indicators of success. Partnerships are rarely evaluated at their incipient stage, which is a critical time to assess their potential for long-term sustainability. In this paper, we present an early-stage evaluative framework for assessing multi-institutional academic partnerships’ sustainability based on 3 dimensions: decision processes, problem orientation, and social capital. We apply the evaluative framework using case study research to the Renewable Energy Assessment (REA) Program, a workforce enhancement academic partnership that focuses on facilities and lands viability assessment. Using the evaluative framework, we identified critical elements present within and missing from the REA Program that could influence the partnership's long-term sustainability. This study demonstrates the need to conduct incipient stage and ongoing evaluations to foster partnership sustainability, and provides a framework for conducting such assessments. 相似文献
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An on-going challenge in teacher education programs is how best to support new teachers in connecting their university coursework with their professional identity development and pedagogical practice in the schools. The reading and writing of case studies is one promising strategy teacher educators have explored as a means of assisting teachers in developing and cultivating a self-reflective, theory and practice reflexive, style of learning in the teacher education classroom and beyond. In the present paper, I present a case study of my own journey as a developmental and educational psychologist responsible for co-teaching a secondary teacher education course called "Adolescent Development for Teachers", in which having student-teachers research and write-up a case study of a single adolescent became the focus of the course and our pedagogy. I describe events that brought about the use of the case study in the course, the influence the use of the case study had on myself as an instructor as well as the students, and what students say are the educational benefits and difficulties of completing the adolescent case study. Implications for infusing a developmental focus into teacher education programs are discussed. 相似文献
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Given the significant negative impacts of peer victimization on youth development, studies have sought to understand what buffers against these consequences. To that end, the present study examined whether teacher attachment and perceptions of school safety moderated the associations between different forms of victimization and school absences over the course of an academic year among a sample of 272 high school students. Findings indicated that teacher attachment moderated the associations between relational and cyber victimization and absences, while perceived school safety moderated associations between relational victimization and absences. However, findings pertaining to cyber victimization were not as anticipated. Implications for prevention and intervention efforts in high schools are discussed. 相似文献
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Harry Adamakos M.A. Kathleen Ryan M.A. Douglas G. Ullman Ph.D. John Pascoe M.D. M.P.H. Raul Diaz Ph.D. John Chessare M.D. 《Child abuse & neglect》1986,10(4):463-470
There is increasing interest in the role of social support in determining risk for child abuse and neglect. The present study assessed the relationship between maternal social support and two areas: stress in the mother-child relationship: and level of stimulation provided in the home. Maternal social support was assessed prenatally and at a two-year follow-up, while the latter variables were compiled at the two-year follow-up. The data were obtained from 38 urban, low SES (80% on public assistance) mothers and their 2-year-old children. Maternal social support correlated positively with level of stimulation and negatively with level of mother-child stress, and was the best predictor of both, relative to any SES, mother or child variables. In addition, high stress, low support mothers provided significantly less stimulation to their children. The theoretical implications for social support as a mediator variable as well as its implications for early identification and prevention efforts in abuse and neglect are discussed. 相似文献
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Pulido R. Martin Seoane G. Diaz Aguado M.J. 《美中教育评论》2010,(1):51-61
This study examines the relation between the social adjustment in the classroom and the role of aggressor or victim, in school violence situations. Participants were 1,635 students (aged 14-18 years old), from a representative sample, with different levels (compulsory secondary education, specific/initial training courses and vocational programs). Students filled out a questionnaire that included measures of types of violence (exclusion, verbal violence, physical violence), from the point of view of the three roles that are implicated (aggressors, victims and observants), and a sociometric questionnaire. The variables measured were: frequency of school violence (exclusion, psychological violence and physical violence) and the peer status (rejected, controversial, neglected, average or popular). The statistic analyses used were χ^2- and F- tests. From the results we can point out the importance of these variables in the school violence situations. The implications of these findings and the relevance for preventive programs are discussed. 相似文献