The neural correlates of working memory training in typically developing children

Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.     

图书馆情报学主要研究方法:了解、选择及使用

[目的/意义]研究方法在学术研究中发挥着至关重要的作用。确认图书馆情报学领域主要的研究方法，并对它们进行了解熟悉，以在开展研究时能合理选择、灵活使用，确保研究质量。[方法/过程]对近2 000篇图书馆情报学领域的研究文献以及相关研究方法论文进行内容分析，在此基础上对研究方法的类分命名、图书馆情报学界主要的研究方法的确定、特点和使用注意事项进行介绍和讨论。[结果/结论]研究方法应以数据收集法而不是数据分析法命名。图书馆情报学领域常用的研究方法包括实验法、问卷法、理论研讨法、内容分析法、访谈法和书目计量法，每种方法都有各自的特点。因而在选择使用时，既应根据具体研究课题及研究方法之特性，也要考虑使用注意事项，并尽量在同一研究中采用两种或更多的方法，以扬长避短，更有效地展开研究。     

Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.     

Digital Module 16: Longitudinal Data Analysis

In this digital ITEMS module, Dr. Jeffrey Harring and Ms. Tessa Johnson introduce the linear mixed effects (LME) model as a flexible general framework for simultaneously modeling continuous repeated measures data with a scientifically defensible function that adequately summarizes both individual change as well as the average response. The module begins with a nontechnical overview of longitudinal data analyses drawing distinctions with cross-sectional analyses in terms of research questions to be addressed. Nuances of longitudinal designs, timing of measurements, and the real possibility of missing data are then discussed. The three interconnected components of the LME model—(1) a model for individual and mean response profiles, (2) a model to characterize the covariation among the time-specific residuals, and (3) a set of models that summarize the extent that individual coefficients vary—are discussed in the context of the set of activities comprising an analysis. Finally, they demonstrate how to estimate the linear mixed effects model within an open-source environment (R). The digital module contains sample R code, diagnostic quiz questions, hands-on activities in R, curated resources, and a glossary.     

Food (in)security communication: a Journal of Applied Communication Research forum addressing current challenges and future possibilities

ABSTRACT

This forum brings together food, (in)security, and communication. The authors participating in this forum center communication as both process and tool for understanding, mitigating, and making meaning of food (in)security. The nine authors together discuss the role of communication in food (in)security, the central challenges for scholars and practitioners working on food (in)security, and the creative possibilities and impacts influencing the future of food (in)security. The forum produces a call for applied scholars to re-imagine communication frameworks in order to make meaningful differences in their communities.     

山东省新泰体操运动学校女子6—7岁组优秀运动员竞技能力各因素相关分析

为提高女子少儿体操运动员选材效果 ,科学地制订运动训练计划以及有效地控制训练的过程 ,对山东省连续两年获得女子 6～ 7岁组团体冠军的新泰体操运动学校 8名优秀运动员 ,进行了身体形态、素质、基本技术等因素各指标的测试 ,用因素分析法探讨了各因素对竞技能力的关联程度。结果表明 ,身体形态匀称即四肢长、手大、髋小、肩宽、体重轻等的女子少儿是较理想的体形 ;素质训练过程中 ,应着重注意增强腹背力量、爆发力和上肢力量 (尤其是支撑力量 ) ;基本技术训练过程中 ,应偏重于自由操翻腾技术的训练 ,这样对其他三项的翻腾技术起到正诱导和促进作用 ,能进一步提高竞技能力。