调血保肾胶囊预防小儿过敏性紫癜肾炎的临床研究

目的探讨调血保肾胶囊预防小儿过敏性紫癜发生发展过程中的肾脏损害,从而降低小儿过敏性紫癜性肾炎的发生率的临床价值。方法设健康组、观察组、对照组,对门诊和住院患儿324例进行临床对比观察,并通过检测尿β2-MG、AIb、TRF、IgG、RBP5种微量蛋白,探讨其预防作用。结果治疗前观察组与对照组尿β2-MG、AIb、TRF、IgG4种微量蛋白均高于健康组（P〈0．01）;而治疗后观察组尿4种微量蛋白与治疗前比较明显降低（尸〈0．05）,对照组与治疗前比较无差异（P〉0．05）;治疗后尿4种微量蛋白观察组与对照组比较亦有差异（P〈0．05）。结论调血保肾胶囊具有预防小儿过敏性紫癜发生发展过程中的肾脏损害、降低小儿过敏性紫癜肾炎发生率的作用,通过尿β2-MG,AIb,TRF,IgG,RBP5种微量蛋白的检测,能够早期发现小儿过敏性紫癜肾脏损害,及时采取预防治疗手段进行有效的治疗。     

规律性有氧运动对肾炎治疗皮脂刺激效果分析

目的:分析规律性有氧运动对肾炎干预治疗与皮脂刺激调节效果,为肾炎干预治疗提供指导。方法:采用统计调查方法总结分析2013年1月到2013年12月医院所干预治疗的1067例慢性肾炎患者的临床资料,治疗过程,按病因分为:肾源性慢性肾炎、相关性慢性肾炎、高脂血症相关性慢性肾炎、手术相关性慢性肾炎、创伤相关性慢性肾炎和其它因素等6个方面进行分析。以病情感染原因将受试对象划分为6组,每组进行不同程度规律性有氧运动干预治疗,通过对于皮脂刺激调节结果统计分析,测定干预治疗效果。结果:规律性有氧运动对肾源性慢性肾炎患者干预治疗,41%患者肾炎感染程度明显减轻,规律性有氧运动对高脂血症相关性慢性肾炎患者干预治疗,38%患者肾炎感染程度减轻,其他因素引起的肾炎,规律性有氧运动干预治疗无明显效果。结论:规律性有氧运动对肾源性慢性肾炎和高脂血症相关性慢性肾炎的干预治疗起到促进恢复作用。     

肾炎：病因不同治法各异

肾炎有肾盂肾炎、肾小球肾炎、间质性肾炎三大类。肾盂肾炎是感染造成的,为尿路感染中的一类;肾小球肾炎是医生通常说的肾炎,是免疫介导的变态反应性疾病,其主要病变发生在肾小球,有一小部分与遗传因素有关;间质性肾炎,则是由于毒性反应侵害肾小管导致的一类肾病。     

肝肾疾病患者血清转铁蛋白和铜蓝蛋白含量的分析

对肝肾疾病进行转铰蛋白(Transferren简称TF)和铜蓝蛋白(Ceruloplasmin简称CP)测定,结果表明:各组肝炎病人的TF均显著低于正常组,且谷丙转氨酶异常和HBsAg阳性者TF含量明显低于正常者,TF可作为判断肝病预后的一个指标。肾炎病人的TF也比正常人低,CP含量各组不一,肝癌患者的CP(52.44±8.73mg％)显著高于正常人(46.75±7.92mg％),乙型肝炎病人和正常组间未见差异.肝豆状核变性患者CP非常显著低于正常人,故检测CP有助于鉴别肝硬化和肝癌,同时对临床诊断肝豆状桉变性提供一项可靠的客观指标.     

谈急性肾小球肾炎的护理体会

急性肾小球肾炎广义上指急性起病急，以血尿、高血压、水肿为主症并常伴有不同程度蛋白尿，肾小球滤过率不同程度下降的一组肾小球疾病患者．对这类患者采取适当的治疗、护理措施尤为重要．     

流式微球阵列术检测V型狼疮性肾炎患者外周血Th1/Th2因子的变化

目的：探讨流式微球阵列术（Cytometric Bead Array,CBA）检测Th1/Th2细胞因子在V型狼疮性肾炎（LN）患者血清中的表达及意义。方法：用CBA法检测20例V型LN患者和20例正常人血清中Th1（TNFα、IFNγ）和Th2（IL-4和IL-5）类细胞因子表达情况。结果：V型LN组Th1类细胞因子TNFα和IFNγ表达均高于正常对照组,而正常对照组中IL-4和IL-5则高于狼疮肾患者,两组中IL-2表达无差异。结论：Th1和Th2类细胞因子平衡/紊乱在狼疮肾患者肾组织损害中可能起一定作用。CBA法检测Th1/Th2细胞因子是一种高效、简便和敏感度高的方法。     

浅谈组织水肿

<正>中学课本、习题和试题中涉及组织水肿的内容较多,本文在对这方面知识进行归纳的同时,并对其发病机理进行简要分析。1营养不良引起组织水肿当摄入的蛋白质较少时,人体缺少必需氨基酸,肝脏合成的血浆蛋白量减少,血浆渗透压降低,使血浆水分进入组织液增多;同时人体细胞合成的蛋白质减少,细胞内液渗透压下降,细胞中的水渗出进入组     

Oxidative stress and damage induced by abnormal free radical reactions and IgA nephropathy

Objective: To estimate the oxidative stress and oxidative damage induced by abnormal free radical reactions in IgA nephropathy (IgAN) patients' bodies. Methods: Seventy-two IgA N patients (IgANP) and 72 healthy adult volunteers (HAV) were enrolled in a random control study design, in which the levels of nitric oxide (NO) in plasma, lipoperoxide (LPO) in plasma and in erythrocytes, and vitamin C (VC), vitamin E (VE) and β-carotene (β-CAR) in plasma as well as the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) in erythrocytes were determined with spectrophotometric mothods. Results: Compared with the HAV group, the averages of NO in plasma, and LPO in plasma and in erythrocytes in the IgANP group were significantly increased (P＜0.0001), while those ofVC, VE and β-CAR in plasma as well as those of SOD, CAT and GPX in erythrocytes in the IgANP group were significantly decreased (P＜0.0001). Linear correlation analysis showed that with the increase of the values of NO, and LPO in plasma and in erythrocytes, and with the decrease of those ofVC, VE, β-CAR,SOD, CAT and GPX in the IgAN patients, the degree of histological damage of tubulointerstitial regions was increased gradually (P＜0.0001); and that with the prolongation of the duration of disease the values of NO, and LPO in plasma and erythrocytes were increased gradually, while those of VC, VE, β-CAR, SOD, CAT and GPX were decreased gradually (P＜0.005). The discriminatory correct rates of the above biochemical parameters reflecting oxidative damage of the IgAN patients were 73.8%-92.5%, and the correct rates for the HAV were 70.0%-91.3% when independent discriminant analysis was used; and the correct rate for the IgAN patients was increased to 98.8%, the correct rate for the HAV was increased to 100% when stepwise discriminant analysis was used. The above biochemical parameters' reliability coefficient (alpha) were used to estimate the oxidative damage of the IgAN patients as 0.8145, the standardized item alpha=0.9730, F=53273.5681, P＜0.0001. Conclusions: A series of free radical chain reactions caused serious pathological aggravation in the IgANP' bodies, thus resulting in oxidative damage in their bodies. In treating IgANP, therefore, it is necessary that suitable dose antioxidants should be supplemented to them so as to alleviate the oxidative damage in their bodies.     

当归黄芪散治疗慢性肾小球肾炎20例

慢性肾小球肾炎是以蛋白尿、血尿、高血压、水肿为基本临床表现，起病方式各有不同，病情迁延，病变缓慢进展，会有不同程度的肾功能减退，最终将发展为慢性肾衰竭的一组肾小球病。临床表现为乏力、疲倦、腰部疼痛、纳差等。     

中医辨证治疗慢性肾炎血尿100例

血尿是慢性肾小球肾炎常见症状之一,西医治疗尚无有效措施,临床治疗较为棘手。自2000年来,笔者运用中医辨证治疗原发慢性肾小球肾炎而致血尿100例,效果较好,现报道如下:1、一般资料本组病例均系2000年1月～2004年3月在我院就诊的门诊住院患者,其中男57例,女43例;年龄5岁～69岁;病程最短1年,最长13年;表现为肉眼血尿与镜下血尿交替者27例;镜下血尿者73例,或伴有不同程度的蛋白尿。其中有43例曾肾穿刺及病理检查:IgA肾病19例;局灶节段性肾炎16例;膜增生肾炎8例。2、治疗方法中医辨证分型论治:(1)风邪袭肺:多见于素有肾病、感邪诱发或加重,恶…