Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.     

大型油船货油装卸仿真模拟装置的开发

运用计算机仿真技术和V isual C 软件设计工具,开发研制基于大型油船货油装卸系统的仿真模拟装置,以供教学与船员培训之用.探讨大型油船货油装卸仿真模拟装置的应用,介绍系统的结构以及软件的实现方法.     

复习C语言应注意的几个方面(之三)——针对CCTC语言函数部分

本文主要针对CCT中的C语言部分,在复习时应该注意的几个方面,以讲、例结合的方式作了详细的论述。     

数量结构的自动识别方案

数量结构是现代汉语中的一个重要组成部分。对于中文信息处理而言,实现其自动识别将对查找中文文本中的重要命名实体有很大的帮助。但从目前的自动识别程序的开放测试结果来看,乃存在错标、漏标等现象。因此,我们在今后的程序的算法设计中还需要进一步的改善。     

浅谈Visual C++中纯资源DLL文件的编写

DLL编程在软件开发中扮演着重要角色。本文介绍了在Visual C＋＋中纯资源DLL文件的编写与调用，实现了应用程序不同语言界面的支持和字符串数据的输出，该方法方便可行，实用性强。     

对民国档案文件级整理工作的思索

在建国后五十多年时间里，档案工作在民国档案整理工作中，遵循档案形成的客观规律，依据全宗原则、利用原基础原则，对全国民国档案进行了案卷级整理工作，逐步建立了包括全宗目录、案卷目录、人名目录、地名目录等在内的民国档案目录体系，部分档案馆还建立了馆藏民国档案案卷级机读目录数据库。不过，随着民国档案开放力度增大，对档案内容信息的揭示提出了更高的要求，原有的民国档案整理成果已难满足现有的民国档案工作需要，对民国档案信息作进一步开发，即开展民国档案件级整理工作已逐渐被提上议事日程，但这项工作对我们来说是崭新的，我们需要对其必要性、和案卷级整理工作的衔接、应结合档案馆数字化工作开展以及在整理人员启用上如何谋求社会力量的支援等等问题加以认真思索。     

基于VC++的自动抽题组卷系统的研究与设计

研究自动抽题组卷系统的策略，重点探讨试题库的构造和抽题组卷策略，提出动态配置组卷参数的算法和随机组卷算法模型。详细介绍试题库子系统、抽题组卷子系统、编制试卷子系统的主要功能，以及基于Visual C++ 6.0的相应的接口。     

基于CPFR策略的需求链管理

当今社会是消费者的社会，如果将消费者需求纳入供应链管理中，以精确的需求预测推动供应链的协调发展，无疑会大大提高企业在市场中的竞争力。而以准确把握市场动态、主动满足消费者需求为核心任务的需求链管理，正是供应链管理发展的新方式。本文以此为切入点，提出了一种基于CPFR策略的需求链管理模型。     

More Than Just a Student Voice: Facilitating Student Leadership Development Through the Library Student Liaison Program

This article explores how the library-student liaison program at Eastern Washington University (EWU) Libraries has evolved into an opportunity for students to develop leadership skills. Originally designed to foster better communication between the EWU Libraries and students enrolled at the university, we recognized that the process of achieving established goals for the program provided a vehicle for students' leadership-skill development. To facilitate the leadership process, librarians employed the Social Change Model. Designed specifically for college students, this model engages the student to develop individual capacities to strengthen group activities that foster positive changes in the community and society.     

影响雪与滑板摩擦系数的几种因数的研究

介绍了雪与滑板的测量系统和利用单片机对数据采集系统。为了提高实验精度,对光电门进行了改进,大大缩短了电平跳变时间,同时对雪与滑板之间的摩擦系数作了比较系统的实验研究。实验结果为制作雪的模型材料提供了基本依据。