新生儿窒息血糖异常50例临床分析

目的 :了解窒息新生儿血糖变化特点 ,为治疗提供依据 .方法 :对 1998年 1月～ 2 0 0 0年 5月收住的窒息新生儿 2 0 4例进行血糖分析 .结果 :2 0 4例中发生血糖异常 5 0例 (2 4 .5 1% ) ,其中低血糖 14例 (6 .86 % ) ,高血糖 36例 (17.6 5 % ) .高血糖的发病率明显高于低血糖的发病率 .高血糖的发生与窒息程度有关 ,重度窒息血糖水平高于轻度窒息 .结论 :对窒息新生儿应严密监测血糖 ,掌握输糖速度 ,避免血糖异常加重脑损伤 .     

运动与血睾酮

血睾酮作为雄性激素的代表，与机体的运动能力有密切的关系。本文综述了血睾酮的生理特点、作用、以及运动对血睾酮影响的研究进展，旨在促进国内体育科学工作者对血睾酮有更深的理解、研究和应用     

罗格列酮和有氧运动对糖尿病糖脂代谢紊乱的干预作用

为探讨罗格列酮和运动对糖尿病糖脂代谢紊乱的干预作用,选用3～4周龄NOD小鼠作为实验材料,分别施加罗格列酮和中等强度有氧耐力运动。通过观察小鼠外在表现、体重和腹部脂肪变化以及胰腺病理切片,检测血清胰岛素水平、血液生化指标,显示罗格列酮和有氧运动对糖尿病糖脂代谢紊乱具有良性干预作用。     

糖尿病与运动研究进展(综述)

对于Ⅰ型糖尿病,运动可作为一种非药物治疗方式,运动在提高胰岛素的敏感性和减少体脂,进而提高葡萄糖吸收等方面已经有诸多研究证实.不管是否合并药物或营养治疗,单独采用合理的运动疗法都可能是有效的,可明显减少Ⅰ型糖尿病患者胰岛素的使用量,但Ⅰ型糖尿病患者从事运动治疗时,可能需要更多的条件和监控.本文对相关的研究进展进行了系统综述.     

一种基于能量谱葡萄糖浓度检测新方法的研究

葡萄糖浓度检测在治疗糖尿病过程中起着重要作用,采用近红外光谱方法测量葡萄糖浓度是国内外研究的热点．通过实验的方法,用800nm到1600nm的近红外光照射葡萄糖水溶液,对不同葡萄糖浓度对应的能量谱进行分析,发现在1111nm处的吸收峰特征比较明显,与葡萄糖浓度有着对应的关系,通过指数曲线拟合,建立葡萄糖浓度检测的数学模型．     

Effects of breakfast with different calorigenic amounts on blood glucose,insulin and glucagon levels

SUBJECTSANDMETHODSSubjectsTwenty four 2 1to 2 4yearsoldhealthymedi calstudentsenrolledinZhejiangUniversityCol legeofMedicinevolunteeredforthestudy .Theyconsistedof1 1malesand 1 3femalesweightsallwithinthenormalrangefortheirheightaccordingtoChinesenorms.Me…     

Effect of obesity and insulin resistance on diabetic control

Diabetes Mellitus in obese and non-obese Indian individuals.AIMS: Effect of Obesity and insulin resistance on diabetic control.SETTINGS AND DESIGN: 50 each groups Diabetic individuals obese and non-obese.METHODS AND MATERIAL: On selected 50 each group diabetic patient and normal, following blood investigations has been performed—Plasma Glucose, Glycohemoglobin and Serum Insulin.STATISTICAL ANALYSIS USED: Individuals patient’s results were analyzed and compared with the normal controls.RESULTS AND CONCLUSION: The changes in glycosylated haemoglobin are mainly proportional to the post lunch glucose level (r=0.773) (p<0.01) and not correlated to circulating insulin or the body mass index. However the levels were higher in obese diabetes (Type I and II both) than in non-obese. Mechanism of resistance in insulin receptor interactions due to obesity is well known. However, obesity does not seem to affect directly glycosylated haemoglobin. Under such circumstances, the reduction of weight for a diabetic person can improve sugar control by minimizing insulin resistance and thereby can improve glycosylated haemoglobin levels.     

Responses to oral glucose challenge differ by physical activity volume and intensity: A pilot study

BackgroundOne-hour postprandial hyperglycemia is associated with increased risk of type 2 diabetes and cardiovascular disease. Physical activity (PA) has short-term beneficial effects on post-meal glucose response. This study compared the oral glucose tolerance test results of 3 groups of people with habitually different levels of PA.MethodsThirty-one adults without diabetes (age 25.9 ± 6.6 years; body mass index 23.8 ± 3.8 kg/m²; mean ± SD) were recruited and divided into 3 groups based on self-reported PA volume and intensity: low activity < 30 min/day of moderate-intensity activity (n = 11), moderately active ≥ 30 min/day of moderate-intensity PA (n = 10), and very active ≥ 60 min/day of PA at high intensity (n = 10). Participants completed an oral glucose tolerance test (50 g glucose) with capillary blood samples obtained at baseline, 15 min, 30 min, 45 min, 60 min, 90 min, and 120 min post-ingestion.ResultsThere were no significant differences between groups for age or body fat percentage or glycated hemoglobin (p > 0.05). The groups were significantly different in terms of baseline glucose level (p = 0.003) and, marginally, for gender (p = 0.053) and BMI (p = 0.050). There was a statistically significant effect of PA on the 1-h postprandial glucose results (p = 0.029), with differences between very active and low activity groups (p = 0.008) but not between the moderately active and low activity groups (p = 0.360), even when baseline glucose level and gender differences were accounted for. For incremental area under the curve there was no significant effect of activity group once gender and body fat percentage had been accounted for (p = 0.401). Those in the low activity group took 15 min longer to reach peak glucose level than those in the very active group (p = 0.012).ConclusionThe results suggest that high levels of PA have a beneficial effect on postprandial blood glucose profiles when compared to low and moderate levels of activity.     

Blood flow restriction in human skeletal muscle during rest periods after high-load resistance training down-regulates miR-206 and induces Pax7

BackgroudBlood flow restriction (BFR) with low-intensity resistance training has been shown to result in hypertrophy of skeletal muscle. In this study, we tested the hypothesis that BFR during the rest periods between acute, high-intensity resistance exercise sessions (70% of 1 repetition maximum, 7 sets with 10 repetitions) enhances the effects of the resistance training.MethodsA total of 7 healthy young men performed squats, and between sets BFR was carried out on one leg while the other leg served as a control. Because BFR was applied during rest periods, even severe occlusion pressure (approximately 230 mmHg), which almost completely blocked blood flow, was well-tolerated by the participants. Five muscle-specific microRNAs were measured from the biopsy samples, which were taken 2 h after the acute training.ResultsDoppler data showed that the pattern of blood flow recovery changed significantly between the first and last BFR. microRNA-206 levels significantly decreased in the BFR leg compared to the control. The mRNA levels of RAC-β serine/threonine-protein kinase v22, nuclear respiratory factor 1, vascular endothelial growth factor, lupus Ku autoantigen protein p70 genes (p < 0.05), and paired box 7 (p < 0.01) increased in the BFR leg. The protein levels of paired box 7, nuclear respiratory factor 1, and peroxisome proliferator-activated receptor γ coactivator 1α did not differ between the BFR leg and the control leg.ConclusionBFR, during the rest periods of high-load resistance training, could lead to mRNA elevation of those proteins that regulate angiogenesis, mitochondrial biogenesis, and muscle hypertrophy and repair. However, BFR also can cause DNA damage, judging from the increase in mRNA levels of lupus Ku autoantigen protein p70.     

耐力和抗阻运动对血脂代谢的影响

长期规律的体育运动均可有效地改善其不良的脂质结构,并能延缓因增龄而带来的不良影响,从而使冠心病的危险性显著降低。目前WHO已将体育运动过少列为冠心病的独立危险因素。因为运动训练对血脂水平的改善起到了至关重要的作用。本综述旨在阐明耐力运动和抗阻运动对血脂代谢的影响。