运动、氧化应激与DNA损伤和修复

在分子和基因水平上对运动时氧化应激损伤、氧化应激与DNA损伤以及DNA损伤和修复等几方面关系进行探讨,旨在探讨运动疲劳和损伤发生的分子生物学基础,并对未来运动医学研究的发展趋势进行展望。     

骨骼肌基因转移系统的建立

以EGFP为标记基因，利用重新构建的pAV-EGFP质粒，采用直接注射方法，进行了离体和在体基因转移研究。实验结果显示，经脂质体包裹后，质粒可以有效地进行细胞转移；DNA表达载体肌肉直接注射后，利用共聚焦显微镜可以在注射点周围的肌细胞观察到绿色荧光蛋白；而在对侧肢PCR和共聚焦显微镜的结果均为阴性。实验结果表明，肌肉直接注射DNA可以在肌肉得到表达，将会为治疗肌肉损伤带来新的方法。     

运动性疲劳分子生物学机制的研究进展

从四个方面(细胞内分子、细胞膜分子、细胞外分子和其他广泛存在的分子和离子)综合分析运动性疲劳分子生物学机制的研究进展,以期达到完善运动性疲劳机制理论体系的目的.     

Light-induced cracking and abrasion of inkjet prints: Damage and mitigation

This study is part of a larger research project at the Image Permanence Institute dedicated to digital print preservation issues – the Digital Print Preservation Portal (DP3). Previous DP3 studies determined that certain digital print types are prone to cracking and/or abrasion, and that factors such as low relative humidity, pollutants, and light increase the brittleness of the ink-receiving layer of some inkjet papers. The purpose of this investigation was to explore if light also increases the propensity of inkjet prints to abrade, and to examine the potential of framing glazings to mitigate light-induced physical damage (cracking and abrasion) by attenuating some portion of the UV spectrum. Inkjet papers and prints were subjected to xenon lighting (to simulate daylight through window glass) without glazing, or in sealed framing packages with plain framing glass (soda-lime) or UV filtering glass. Before and after light exposure, brittleness, and abrasion resistance were evaluated independently using two tests: ISO 18907 (Imaging materials – Photographic films and papers – Wedge test for brittleness) and a rub test utilizing a Sutherland® Rub Tester. In this study, exposure to light increased the cracking and/or abrasion tendency of some specimens. The use of UV filtering glass reduced this light-induced propensity in all cases. Plain glass protected all samples from at least one of these two types of surface damage, but was less effective than UV glass. Light-induced brittleness and sensitivity to abrasion were mostly, though not exclusively, caused by UV radiation. It was also seen that some prints may become brittle and/or prone to abrasion in the absence of image fade. Budgeting the amount of light these objects can be exposed to, protecting them from UV radiation, and handling prints with caution especially after exhibition, is essential in order to limit physical damage.     

机动车交通事故损害赔偿责任的构成要件研究

我国机动车交通事故损害赔偿责任的构成要件,除包括机动车交通事故致人损害事实、机 动车交通事故致人损害行为的违法性,以及机动车侵权行为与损害事实之间的因果关系等一般要件,还 应包括道路要件、车辆要件、交通要件和人身损害赔偿要件等特别要件。     

DNA生物大分子的动力学特性与生物功能(Ⅱ)

对ＤＮＡ中激发的孤立子进行了分类，同时也研究了它的一些特点．我们着重研究了用此理论解释ＤＮＡ的基本生物功能──复制和转录及遗传与变异等问题．     

建筑抗震概念设计

本文从建筑的平立面布置、抗震结构体系、结构构件和非结构构件设计等方面阐述了建筑抗震概念设计的一般原则和规律     

雷电损坏电视机的机理分析

本文运用电磁感应原理分析了雷电的电磁效应及产生原理,阐明了雷电感应具有大电流、高电压的特点和雷电所产生的电磁场具有高频电磁波的性质,论述了雷电损坏电视机的机理和避雷防雷措施。     

关于泄洪洞水力设计中空蚀问题的探讨

首先介绍了空蚀破坏的原理以及发生空蚀破坏的条件，并分析了龙抬头式泄洪洞发生空蚀破坏的原因和易发生空蚀破坏的部位。最后，结合工程实例的实验结果，说明了发生空蚀破坏的主要原因是不平整度以及体型的不合理。     

精神损害的国家赔偿责任

精神损害的国家赔偿是国际上许多国家和地区的立法趋势,而我国的《国家赔偿法》却并没有对此做出相应的金钱或者物质赔偿的规定。面对现实生活中行政权的滥用,为了确保公民的权利得到有效的保障,构建国家赔偿中的精神损害赔偿制度是中国法律发展的必然目标。