发育性颈椎管狭窄与脊髓型颈椎病的相关性分析

目的：进一步探讨脊髓型颈椎病与发育性颈椎管狭窄的关系。方法：应用比值法对70例正常人和110例脊髓型颈椎病患者的X线侧位片进行统计学测量与比较，研究范围从C3～C7。结果：C3～C7正常组与颈椎病组的椎管中矢径比值有显著性差异。结论：发育性颈椎管狭窄是脊髓型颈椎病的重要发病因素。     

Challenging from the margins into the mainstream—improving renal services in a collaborative and entrepreneurial spirit

Can the development, both clinical and managerial, of practitioners involved in healthcare be enriched by connecting action learning principles and practice with research on ‘tempered radicals’? Might such connection also assist the efforts of patients and their advocates to create more holistic approaches to patient care? This paper explores these questions with reference to a UK Department of Health project to improve renal services. The prime focus is the experience of a set of set advisers who ‘held the ring’ on the project, supporting the work of the sets and attempting to make sense of the emerging learning.     

Off-pump coronary artery bypass grafting versus on-pumpcoronary artery bypass grafting: which is better in patients with chronic obstructive pulmonary disease?

INTRODUCTION Conventional coronary artery bypass graftin(CCABG) with cardiopulmonary bypass (CPB) habeen accepted as an effective and safe treatment fomulti-vessel coronary heat disease. CPB may stilcontribute to the operation field because of threlatively easier technical requirement; but it alscauses a serious systematic inflammatory reactiowhich will lead to dysfunction of important organand higher cost for the patients. Off-pump coronarartery bypass grafting (OPCABG) has r…     

肱动脉血压相关因素的研究

利用20天的时间,每天10:00到15:00随机抽查,测量本校1000名大学生(男女生各500人)左右侧肱动脉血压的差异性;测量江苏省徐州市醒狮居民小区居民500名(男女各250人),年龄在20至69岁之间,探究血压与年龄和性别之间的关系。在大学生组中,将测量所得的结果通过χ2检验,u检验,其p值均大于0.05;典型相关分析检验中,相关系数约为1,说明大学生左右肱动脉血压无显著差异。在居民组中,运用matlab 7.0对数据进行拟合,结果显示随年龄的增长,舒张压、收缩压均逐渐升高,且收缩压的增长要大于舒张压的增长,男性的脉压整体高于女性,大约在45岁之后,双方差异逐渐减小。     

苏州地区中年男性动脉弹性现状及影响因素的调查分析

对苏州地区214名中年男性动脉弹性现状及影响因素的调查与分析结果显示:214名受试者中仅10.7%为动脉弹性正常者,其他89.3%均有动脉弹性不同程度的下降。体育锻炼与饮食习惯是导致动脉弹性变化的重要因素(P<0.05)。经常参加体育锻炼可以降低动脉血管硬化的风险,高胆固醇和高盐饮食则增加动脉血管硬化的发生风险。     

Potential Chemoprevention of 7,12-Dimethylbenz[a]anthracene Induced Renal Carcinogenesis by Moringa oleifera Pods and Its Isolated Saponin

Present investigation shows that hydroethanolic extract of Moringa oleifera (MOHE) and its isolated saponin (SM) attenuates DMBA induced renal carcinogenesis in mice. Isolation of SM was achieved by TLC and HPLC and characterization was done using IR and ¹H NMR. Animals were pre-treated with MOHE (200 and 400 mg/kg body weight; p.o), BHA as a standard (0.5 and 1 %) and SM (50 mg/kg body weight) for 21 days prior to the administration of single dose of DMBA (15 mg/kg body weight). Administration of DMBA significantly (p < 0.001) enhanced level of xenobiotic enzymes. It enhanced renal malondialdehyde, with reduction in renal glutathione content, antioxidant enzymes and glutathione-S-transferase. The status of renal aspartate transaminase, alanine transaminase, alkaline phosphatase and total protein content were also found to be decreased along with increase in total cholesterol in DMBA administered mice. Pretreatment with MOHE and SM significantly reversed the DMBA induced alterations in the tissue and effectively suppressed renal oxidative stress and toxicity.     

Evaluation of urinary abnormalities in nephrolithiasis patients from Marathwada region

Urinary abnormalities were evaluated in 100 renal stone patients with first episode of renal stone having age 22 to 45 years from both sex and compared to 100 normal healthy control group having same age group from both sex. Twenty-four hours urinary oxalate, calcium, uric acid, sodium, magnesium, phosphorus and citrate were estimated. The urinary pH was also determined. In stone formers urinary oxalate, calcium, sodium and uric acid excretions were significantly higher when compared with control group. Whereas citrate, phosphate and magnesium excretion were significantly lower in stone formers when compared with control. The pH of urine in stone formers was lower than the controls. High dietary intake of purine rich diet causes elevated excretion of uric acid, which leads to calcium oxalate crystal formation and precipitation. Other risk factors such as urinary oxalate, calcium also related to formation of renal calculi. Hypocitraturia is the main cause of renal calculi along with hypomagnesiuria and hypophosphaturia in the patient of Marathwada region. On the basis of urinary abnormalities further stone formation in the patient can be prevented by dietary modifications.     

肾综合征出血热病后残留损害的研究(Ⅱ)

在1988年5月对HFRS病后1～10年148例调查的基础上,对其中的77例进行了第二次调查.结果:全身乏力占68.83％,头昏痛占48.05％,腰痛占41.55％,背胀占37.66％,心悸气短占20.77％.19例血清和/或尿液β_2-MG异常的患者,此次仍有6例血清β_2-MG大于3000ng/ml,9例尿β_2-MG大于150ng/ml,4例尿Alb,5例尿IgG,3例尿NAG异常.     

血浆纤维蛋白原水平升高同高血压,冠心病及卒中的联系

选择46岁以上的高血压(HBP)、冠心病(CHD)、卒中及其它内科住院病人共140名进行了血浆纤维蛋白原(FG)、血压、甘油三酯(TG)和吸烟等因素的观察.结果表明高血压、冠心病和车中患者FG值升高,逐步回归分析看出吸烟,HBP和TG水平升高明显影响FG的含量,提示FG水平升高同HBP,CHD和年中存在着紧密的联系。     

Standardization of a dilution method for cyclosporin (C2) estimation in renal transplant patients

Accurate monitoring of blood cyclosporin C2 levels is vital to prevent over immunosuppression and acute renal toxicity in patients who receive organ transplant. The matrix used to dilute patients’ C2 samples prior to the assay affected the final measured values. Hence there was a need to develop a method of dilution that would accurately estimate C2 levels when cyclosporin levels were beyond the calibration range of the method employed. Whole blood, cyclosporin free hemolysate and cell and protein free supernatant obtained after pretreatment of normal blood were used to dilute patients’ C2 samples. C2 was measured in 188 patients using the supernatant method of dilution. C2 was correlated with Co and dose of cyclosporin received by the patient. The use of cell and protein free supernatant obtained after pretreatment of normal blood as a C2 diluent detected higher levels of C2 in the sample. Measured C2 correlated significantly with Co and the cyclosporin dose received by the patient. The uniformly aqueous cell and protein free supernatant ensures uniform dilution of the patients’ C2 sample and measures higher cyclosporin levels.