太极拳对老年人心肺机能的影响

通过系统观察、测试部分长年参加太极拳练习者和无训练者在完成定量负荷运动前后心肺功能指标变化,发现长期进行太板拳练习的老年人心脏泵血功能、心肌收缩机能、肺活量均显著优于普通人,表明长年从事太极拳运动对促进老年人心肺功能的改善具有积极作用,为老年人参加太极拳运动提供了可靠的实验依据.     

对不同项群运动员运动负荷前后左心室舒张功能的观察

为了评价不同项群运动员左心室舒张功能,对12名耐力项目运动员和12名速度力量项目运动员12min前后二尖瓣血流频谱进行了检测。结果表明:12min跑后耐力组血流速度积分和E/A明显减小,速度力量组血流速度积分、E峰值和E/A减小十分明显,A峰值减小明显,两组运动员血流速度积分、E峰值和E/A存在显著差异。说明,耐力组左心室舒张主动松驰及被动充盈能力均好于速度力量组。     

散步对中老年高级知识分子心脏功能影响的追踪分析

对采用散步作为锻炼手段的40名中老年高级知识分子的心脏功能指标进行追踪测试，显示散步可使中老年高级知识分子的PR、HOV、HOI降低；SV、SI、VPE、EWK升高；而对于CO、CI、LVWI的影响较小。提示坚持散步对提高中老年高级知识分子的心脏功能有较好的作用。     

心衰康煎液对阿霉素心衰模型大鼠心肌的影响

目的观察中药复方制剂"心衰康煎液"对心衰大鼠心脏血流动力学的影响及心肌细胞的病理学改变.方法利用pclab实验记录分析系统观察和分析各实验组大鼠左心室内压、对大鼠心肌切片H.E染色镜下观察.结果心衰康使心衰得到明显改善,心肌细胞无明显变性、坏死.结论中药复方"心衰康煎液"对心衰大鼠的心肌病变有明显改善,从而产生良好的抗心衰作用.结论     

Alterations in autonomic cardiac modulation in response to normobaric hypoxia

Purpose: The present study aimed to determine if autonomic cardiac modulation was influenced by acute exposure to normobaric hypoxia. Method: Ten healthy male lowland dwellers completed five block-randomised single-blinded, crossed-over acute exposures to a normobaric hypoxic environment, each separated by 24 hours’ recovery (20.3%, 17.4%, 14.5%, 12.0% and 9.8% F_IO₂). Supine recordings were made of arterial oxygen saturation and electrocardiogram (ECG). RR intervals from the ECG trace were analysed for time (SDNN, lnrMSSD), frequency (lnVLF, lnLF, lnHF, lnTP, LFnu, and HFnu), and nonlinear (DFA-α1 and SampEn) heart rate variability components. Results: A significant reduction in arterial SaO₂ occurred with reduced F_IO₂, along with a rise in heart rate (Cohen’s d?=?1.16, 95% Confidence Interval [2.64–6.46]), significant at 9.8% F_IO₂. A decrease in autonomic cardiac modulation was also found as shown by a statistically significant (at 9.8% F_IO₂) decrease in lnTP (d?=?1.84 [1.74–1.94]), and SampEn (d?=?0.98 [0.83–1.12]) and an increase in DFA-α₁ (d?=?0.72 [0.60–0.84]) from normoxia at 9.8% F_IO₂. Conclusion: The decrease in variability indicated a reduction in autonomic cardiac modulation. There appears to be a threshold ～9.8% F_IO₂ (～6000?m equiv.), below which significant alterations in autonomic control occur.     

心安灵对麻醉犬心肌缺血的保护作用

目的:观察心安灵对冠脉结扎麻醉犬的保护作用.方法:麻醉犬冠脉结扎复制心肌缺血模型.观察给药后ST段偏移总和(Σ-ST)、ST段抬高≥2mv的个数(N-ST)、LDH、CK释放的变化.结果:心安灵可显著减少冠脉结扎所致的Σ-ST抬高和N-ST增加,同时减少血清中LDH和CK的释放.结论:心安灵对麻醉犬冠状动脉结扎所致的心肌缺血具有明显改善作用.     

Cardioprotective activity of synthetic guggulsterone (E and Z-isomers) in isoproterenol induced myocardial ischemia in rats: A comparative study

Guggulsterone, a mixture of cis (E) and trans (Z) isomers (7∶3 w/w) was synthesized from 16-DPA. The isomers were separated by column chromatography and evaluated for cardioprotective and antioxidant activities. Myocardial necrosis induced by isoproterenol in rats caused marked increase in serum creatine phosphokinase and glutamate pyruvate transaminase. Simultaneously in ischemic heart, phospholipase, xanthine oxidase and lipid peroxides were enhanced following depletion of glycogen, phospholipids and cholesterol. Treatment with guggulsterone and its both isomers at the dose of 50 mg/kg po., significantly protected cardiac damage as assessed by the reversal of blood and heart biochemical parameters in ischemic rats. The cardioprotective activity of guggulsterone and of both the isomers were compared with that of gemfibrozil at the same doses. Guggulsterone and both the isomers at tested concentrations (5–20mM) inhibited oxidative degradation of lipids in human low-density lipoprotein and rat liver microsomes induced by metal ionsin vitro. The drug counteracted against the generation of superoxide anions (O₂) and hydroxyl radicals (OH⁻) in non-enzymic test systems. It is suggested that cardioprotective and antioxidant activities of synthetic guggulsterone and guggulsterone obtained from gum resinCommiphora mukul that contains isomers E & Z in the ratio of 46∶54w/w are the same.     

基于多普勒频谱图的力量项目运动员左室舒张期室壁运动研究

通过测定和比较正常人和力量项目运动员在静息和逐级递增负荷运动时,室壁多普勒频谱图上E波和A波峰值速度,研究左室后壁主动松弛和被动充盈功能的变化。结果表明：在静息状态,力量项目组房缩期心房收缩对于左室舒张充盈的贡献小于正常组;在逐级递增负荷中,力量项目组心脏舒张功能的动员表现为同时动用主动舒张储备和左房收缩储备,显示出心脏主动舒张的能力强,左房收缩储备大。     

运动与细胞凋亡

细胞凋亡的研究是运动科学中一个较新的领域.近年来,运动领域的科学工作者对运动与骨骼肌细胞、心肌细胞、淋巴细胞、肝细胞凋亡关系进行了研究,并对运动引发细胞凋亡的机制进行了探讨,但研究结果有一定的差异,关于运动与细胞凋亡的关系还需要更深层次的研究.     

运动训练对心脏远期效应的超声研究

以34名上海体育学院退休体育教师为实验组,同济大学普通退休,并较少参加体育活动的老年人32名为对照组,利用彩色多普勒超声心动图检查获得66名60~79岁老年人的心脏形态及功能指标,普通老年人经体表面积BSA校正后得到的心脏结构指标指数据值中多数大于曾有青年期运动史的老年人。心脏功能指标中,曾有青年期运动训练史的老年人的LVFS(P<0.05)、LVFS(P<0.05)、SV(P<0.01)、CO(P<0.05)大于普通老年人,MVE/A(P<0.05)、HR(P<0.01)小于普通老年人。曾有青年期运动训练史的老年人心脏结构和功能随增龄的减退要缓于普通老年人。