米索前列醇用于晚期妊娠促宫颈成熟与引产的效果分析

为了观察晚期妊娠引产使用米索前列醇的可行性、有效性和安全性,选择有引产指征、无米索前列醇使用禁忌证的胎膜完整、单胎、头位晚期妊娠妇女150例,随机分为A、B两组,其中米索组80例,缩宫素组70例,并且对该两组引产时效、母儿并发症的发病情况作分析比较．结果表明：米索组较缩宫素组可明显改善宫颈成熟度,缩短引产至分娩时间（P〈0．01）,两组母儿并发症差异均无统计学意义（P〉0．05）．因此,在严格掌握米索前列醇引产的适应症情况下米索前列醇用于晚期妊娠引产及促宫颈成熟有价格低、性质稳定、易于保存、效果肯定,安全易掌握、引产成功率高等优点,值得临床推广尤其适合基层医疗机构应用．     

The Freedom to Birth—The Use of Cytotec to Induce Labor: A Non-Evidence-Based Intervention

The off-label use of Cytotec (misoprostol) to induce labor has increased over the past few decades. The increase in medical interventions in childbirth, many of which are not based on scientific evidence, and the rise in maternal and infant morbidity and in maternal and infant mortality cannot continue to go unrecognized. This column serves as a teaching tool for childbirth educators and provides an example of two unnecessary, potentially avoidable deaths that occurred during a birth with questionable medical interventions.     

米索前列醇用于晚期妊娠引产的效果研究

目的探讨米索前列醇对晚期妊娠引产的有效性和安全性。方法选择有引产指征、无引产及米索前列醇使用禁忌证的单胎、头位、胎膜完整的晚期妊娠妇女103例,随机分为A组(48例,米索前列醇)和B组(55例,催产素)。结果A组与B组引产成功率分别为77.08%、72.73%。首次用药至临产时间分别为6.18h、12.3h,首次用药至阴道分娩时间分别为369.23±235.90h、430.00±211.31min,有显著性差异(P<0.05)。分娩方式、新生儿体重,两组比较,差异均无显著性(P>0.05)。结论米索前列醇用于晚期妊娠引产有效而且安全。