胎盘源细胞治疗急性辐射骨髓衰竭研究

核辐射易造成人体造血系统损伤,为此建立急性辐射骨髓衰竭小鼠模型,通过单次腹腔注射异基因小鼠多份不同胎盘源细胞／细胞因子,明确其治疗急性辐射骨髓衰竭的疗效．实验将造模后小鼠随机分为胎盘源细胞治疗组、胎盘源细胞因子治疗组、胎盘源细胞联合细胞因子治疗组以及模型小鼠对照组4组,治疗后统计分析各组小鼠存活时间．结果表明,胎盘源细胞联合细胞因子可有效延缓急性辐射骨髓衰竭小鼠的寿命（P ＜0．05）．     

当阳峪绞胎艺术瓷的装饰特色

当阳峪绞胎艺术瓷是我国陶瓷史上的一枝奇葩，以“剔花”称，绞胎取胜，绞胎、绞釉、剔花的技法特点，更具地方特色。     

晚期产后出血69例临床分析

[目的]分析探讨晚期产后出血原因,以利于临床晚期产后出血的预防和控制.[方法]回顾分析医院1995年1月~2004年2月9年来收治晚期产后出血69例,分析出血原因及治疗措施和预后.[结果]69例晚期产后出血,其中胎盘胎膜残留18例;子宫复旧不良38例;产褥感染13例.晚期出血原因主要是子宫复旧不良,其次是胎盘残留和产褥感染.[结论]晚期产后出血发生率逐渐下降,但剖宫产术后引起晚期产后出血呈上升趋势值得引起重视.     

MCP-1在子痫前期患者胎盘组织及血清中的表达及意义

通过比较单核细胞趋化蛋白-1(MCP-1)在正常孕妇和子痫前期患者胎盘及血清中的表达,探讨MCP-1在子痫前期发病机制中的作用。选取30例正常晚孕妇女、30例轻度子痫前期患者和30例重度子痫前期患者进行研究。采用免疫组织化学S P法检测MCP-1在胎盘组织中的表达;采用酶联免疫吸附法(ELISA)检测血清MCP-1水平。结果:子痫前期患者胎盘组织和血清中MCP-1的表达均高于正常妊娠组,差异有统计学意义(P<0.01),且随着病情加重而递增;子痫前期患者胎盘组织MCP-1表达与血清MCP-1水平呈显著正相关(r=0.725,P<0.01)。结果表明,MCP-1在子痫前期患者胎盘与血清中的表达均升高,提示MCP-1在子痫前期的发生、发展中可能起着重要的作用。     

植入性胎盘保守治疗10例体会

目的运用甲氨蝶呤、米非司酮及中药保守治疗,观察非手术治疗植入性胎盘的疗效。方法米非司酮50mg口服,2次/d,共服5d;甲氨蝶呤20mg,1次/d,肌肉注射,连用3d;5天后口服中药生化汤加味。结果 10例植入性胎盘患者住院7～24d,均痊愈出院。结论保守治疗对植入性胎盘是可行的。     

More Than Clinical Waste? Placenta Rituals Among Australian Home-Birthing Women

The discursive construction of the human placenta varies greatly between hospital and home-birthing contexts. The former, driven by medicolegal discourse, defines the placenta as clinical waste. Within this framework, the placenta is as much of an afterthought as it is considered the “afterbirth.” In home-birth practices, the placenta is constructed as a “special” and meaningful element of the childbirth experience. I demonstrate this using 51 in-depth interviews with women who were pregnant and planning home births in Australia or had recently had home births in Australia. Analysis of these interviews indicates that the discursive shift taking place in home-birth practices from the medicalized model translates into a richer understanding and appreciation of the placenta as a spiritual component of the childbirth experience. The practices discussed in this article include the burial of the placenta beneath a specifically chosen plant, consuming the placenta, and having a lotus birth, which refers to not cutting the umbilical cord after the birth of the child but allowing it to dry naturally and break of its own accord. By shifting focus away from the medicalized frames of reference in relation to the third stage of labor, the home-birthing women in this study have used the placenta in various rituals and ceremonies to spiritualize an aspect of birth that is usually overlooked.     

宫颈环扎术治疗中央性前置胎盘的护理体会

目的：为了提高宫颈环扎术治疗中央性前置胎盘的效果，降低围产儿死亡率，并揭示临床护理工作在医疗工作中的自身独特优势。方法：采用心理护理观察，药物、手术治疗护理观察，技术操作处置护理等等。结果：临床护理观察在医疗工作中起重要作用，配合治疗本案21例，平均保胎34．9天，出生婴儿均成活。     

酶水解法加工牛胎盘的工艺研究

研究了酶法加工牛胎盘时酶的选择、水解时间、水解温度及原料的预处理等工艺条件。结果表明，多种蛋白酶的处理均能大幅度提高产品回收率，最佳的应用条件是每克原料加入400u中性蛋白酶，pH为7.8时40℃或45℃水解60min。     

Telomerase RNA and telomerase activity in trophoblastic tumors

To gain better understanding of telomerase’s possible role in the carcinogenesis of gestational trophoblastic tumors, the authors conducted RT-PCR amplification-based analysis and carried out telomeric repeat amplification to determine the levels of the human telomerase RNA (hTR) and that of telomerase enzymatic activity itself in 43 normal human placental tissues, 35 gestational trophoblastic tumor tissues and three choriocarcinoma cell lines. hTR was expressed in malignant gestational trophoblastic tumor tissues as well as choriocarcinoma cell lines. The results showed that hTR of early placenta villi and a part of hydatidiform mole were positive. But relatively low levels of the hTR could be found in placental tissues. Telomerase enzymatic activity was strongly positive in 32 of the 35 (91.4%) gestational trophoblastic tumor tissues and all the three choriocarcinoma cell lines. The enzymatic activity of telomerase itself was detectable at relatively low lelves in 14 of the 21 (66.7%) early placental villi, only three of the 22 (13.6%) term placenta were weakly positive. These results suggest that telomerase activity may be correlated with the development of trophoblastic tumors, and so, may be a useful diagnostic marker for detecting the existence of malignant trophoblastic cells. Project (39670753) supported by NSFC     

TELOMERASE RNA AND TELOMERASE ACTIVITY IN TROPHOBLASTIC TUMORS

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