Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.     

低应变法检测桥梁嵌岩桩的评价

用低应变法检测嵌岩桩 ,若桩底出现明显同相反射 ,多数因桩底缺陷引起。而区分是桩还是持力层的缺陷 ,主要看反射的起跳时间在 2 L/ C之前还是之后。当桩的变径及入岩反射对测试影响很大时 ,应进一步用钻芯法检验。     

Steps Toward More Effective Implementation of the Standards for Educational and Psychological Testing

The goal of the Standards for Educational and Psychological Testing is to improve testing practices, but their impact on practice appears spotty. Self-regulation clearly fails in some instances. The establishment of an external agency to oversee testing practices and adherence to the Standards would face substantial hurdles, and the ambiguity of many of the Standards would hobble such an organization if one were created. Many of the Standards are general statements of principle, and past controversies make clear that we in the field often disagree about the reasons for them, their applicability to specific cases, and their practical meaning in specific contexts. This paper argues that the field should follow two approaches to lessen this ambiguity. First, using journals, conferences, and other vehicles, we should foster more frequent and more protracted debate about the practical meaning of key Standards, such as 13.6 and 13.7, which mandate that a decision that will have a "major impact" on a student should not be based on a single score. Second, future revisions of the Standards should use concrete examples of testing practices to clarify the meaning of the Standards, much as the legal system uses case law to clarify the meaning of the general principles embodied in statutes .     

投篮质量评价标准建立及应用

分析按命中率评价投篮质量这一方法不利于运动队 (员 )之间投篮水平的变化及技战术水平发挥程度的比较。提出了将投篮按结果不同分为 A、B、C、D四级 ,用于定量分析投篮技术水平的新的投篮质量评价标准 ,介绍了新的投篮质量评价标准在 CBA决赛阶段的应用。     

从事物特性的相互作用本质看运动生物力学研究方法与测试手段的发展

从任何事物的特性都是由相互作用相互联系的的事物双方共同决定的这一哲学原理来看,运动生物力学的研究方法和测试手段发展具有主动性,它能够从运动中的人体引申出这样或那样的特性来,能够引申出何种特性不仅取决于运动中的人体,也取决于研究方法和测试手段,从而推动运动生物力学学科的发展。     

On Applicable Methods in Testing Spoken English

The importance of raising speaking ability of the students is more and more emphasized. But the pity is that, until present time, teachers or testers have to face the perplexity of lacking useful ways to test the students about their ability in speaking. In order to break through the existing perplexity, the author tries, by analyzing the applicability of several methods for testing this ability, to shade a new light in this field, thus facilitate the means of daily teaching and learning evaluation.     

武汉体育学院学生身体素质测试指标、方法和结果研究

研究分析武汉体育学院学生身体素质测试指标、方法、过程与结果。结合体育院校学生特点,对学生身体素质指标进行了测试,并就选择学生身体素质测试的原则、依据、测试指标的构建和方法的确立等进行探讨。制订身体素质测试指标和评价标准,结果表明:学生身体素质测试指标与评价标准符合在校学生身体素质的实际,达到了预期的目的与效果。     

Creating Better Learners Through Learning Science: A Sample of Methods

This article proposes the incorporation of learning science into the programming and operation of public libraries. Learning science, a multidisciplinary field spanning cognitive science, psychology, neuroscience, economics, anthropology, and linguistics, has identified proven methods for enhancing learning at any age. The article highlights some of the tools and insights that are most relevant to libraries in their role as centers for informal learning.     

Fake news,fake truth: A new purpose for public schooling

The world is adversely affected by the plethora of easily available fake and misleading information. Public schools are established to help generate responsible citizens.Public schools may have a role to play in addressing the fake news, fake truth problem.     

Teaching principles of inference with ANOVA

Analysis of variance (ANOVA) is a test of mean differences, but the reference to variances in the name is often overlooked. Classroom activities are presented to illustrate how ANOVA works with emphasis on how to think critically about inferential reasoning.