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1.
目的:探讨不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制。方法:将雄性Wistar大鼠50只随机均分为5组:安静对照组(C)、低负荷运动训练组(LT)、中等负荷运动训练组(MT)、高负荷运动训练组(HT)和极高负荷运动训练组(ST),每组10只。各运动组分别进行6周的跑台运动训练。训练方案结束后,取腓肠肌样本,提取线粒体,测定线粒体柠檬酸合成酶(CS)、异柠檬酸脱氢酶(ICD)和α-酮戊二酸脱氢酶(α-KGDHC)活性;线粒体Ga2+含量、胞浆NADH、NAD+、ATP和ADP含量,以及ICD mRNA转录水平。结果:(1)不同负荷运动训练组线粒体CS、ICD和α-KGDHC的活性均显著高于安静对照组(P < 0.01),且CS和ICD活性由高到低顺序均为:MT组 > HT组 > ST组 > LT组 > C组,α-KGDHC活性由高到低顺序为:HT组 > MT组 > ST组 > LT组 > C组。(2)不同负荷运动训练组线粒体Ca2+ 含量均显著高于安静对照组(P < 0.01),其含量由高到低顺序为:MT组 > HT组 > ST组 > LT组 > C组;胞浆NADH/NAD+和ATP/ADP的比值均显著低于安静对照组(P < 0.01),其比值由低到高顺序为:MT组 < ST组 < HT组 < LT组 < C组。(3)不同负荷运动训练组ICD mRNA转录水平均高于安静对照组(P < 0.01),其水平由高到低顺序为: MT组 > HT组 > ST组 > LT组 > C组。结论:低负荷、中等负荷、高负荷及极高负荷运动训练均可提高大鼠骨骼肌线粒体三羧酸循环功能,且中等负荷运动训练效果最佳。其机制与胞浆NADH/NAD+和ATP/ADP比值、线粒体摄钙能力及限速酶基因的表达有关。 相似文献
2.
Vasilis Grammatikopoulos Athanasios Gregoriadis Michalis Linardakis 《Educational Measurement》2019,38(3):46-54
Self‐reported measures are an easy, time‐efficient, and low‐cost way to collect research data compared to other assessment methods. They are, however, characterized by several limitations regarding the quality and the clarity of the data they produce, especially when they are implemented in education. The main purpose of the current study was to use a method called discrete choice modeling (DCM) in education, in order to develop a self‐reported instrument that will reduce the bias for socially desirable responses and to assess teachers’ practices in physical activity. DCM method has the ability to overcome the respondents’ tendency to answer in a socially desirable way. A nationally representative sample of 531 Greek early educators participated in this study and were administered a self‐assessment questionnaire based on DCM. Results showed that the DCM based newly developed instrument manages to assess effectively educators’ practices and provided evidence of the applicability of the method in education. Further implications and future recommendations regarding the effective application of DCM in education are discussed. 相似文献
3.
Laurel Kristick 《资料收集管理》2020,45(2):151-161
AbstractDiversity literary awards and other sources were used to create a list of high-quality titles written by and about underrepresented groups. This list was used to assess the diversity and inclusiveness of the library collections of a land-grant university in the Pacific Northwest and compare it to peer institutions. Gaps in the collection and acquisition processes were identified and will be used to improve the processes to increase the number of diverse titles added to the library’s collections. 相似文献
4.
Abstract This paper provides a methodology to study the characteristics of the research output from a university department. The faculty publications and their cited references over a 10-year period were used as the basis for this study to identify their publishing patterns and the types of material they are publishing; a core set of journals and other resources they are publishing in and citing over this period; the characteristics of the journals in which they publish and cite; the degree of openness of their publications and their citation advantage; and the age of resources that are referenced. 相似文献
5.
采用文献资料法、调查法、因素分析法和实验法,对足球专修学生成绩的评定问题进行了比较系统的综合研究,为制定评定学生足球专项成绩体系和权重等提供了客观依据。建立了技、战术考核评分模式。 相似文献
6.
7.
Keith Park 《British Journal of Special Education》2004,31(1):16-23
Keith Park, advisory teacher for Sense (the National Deafblind Rubella Association) in Greenwich and Lewisham, London, has written about his approach to interactive storytelling for BJSE before. This article describes a series of poetry workshops based on chapters 37 to 45 of the Book of Genesis (the story of Joseph and his family) using the text of the King James Bible of 1611. The workshops took place at Charlton School in Greenwich between September and November 2002. The full text of the Genesis workshops, with a clear exposition of their implementation, is provided here but the article begins with a restatement of the principles of interactive storytelling. The importance of developing curriculum access for pupils with multi-sensory impairments while simultaneously supporting staff who work with these young people in schools is emphasised. Keith Park discusses the relevance of the circle concept in storytelling and the strong focus, in the poetry workshops, on rhythm. He goes on to evaluate the impact of the workshops, both in terms of staff confidence and through examples of the pupils' responses mapped against the Qualifications and Curriculum Authority (QCA) framework for recognising the attainments of pupils with learning difficulties. The article concludes with some indications of further developments in this exciting and innovative area of practice. 相似文献
8.
网络从根本上影响着人们的生活,影响着人们的人生观。目前,网络社会中的人生观具有多样性、背叛性、极端性和从属性。为此,必须加强网络社会的人生观教育,改进当前社会的思想工作方式。 相似文献
9.
本文详细论述了FANUC-OTDII系统G70-G76指令的应用,并依据其应用场合给出针对性的实例。 相似文献
10.
长拳中的腾空旋风脚720°的动作技术分析 总被引:1,自引:0,他引:1
对安徽省武术队运动员的C级难度动作--腾空旋风脚720°技术动作进行高速摄影,通过图片分析,结合多媒体技术、分析完成该技术动作的相关技术的关系,以便指导训练,提高运动员的运动水平. 相似文献