Covid-19: Emerging Considerations for Body Sourcing and Handling. A Perspective View from Nigeria

The current Coronavirus disease (Covid-19) pandemic has spread to about 220 countries of the world and has resulted in a significant number of deaths globally. Infections are still on the rise, and the impact on the global death rate could be devastating. There are fears over the likely impact of a large number of deaths on body sourcing and handling of cadavers for teaching and research. Historically, epidemics come with several challenges and have often led to some level of negligence of ethical practices and health and safety regulations associated with body sourcing and handling. The authors highlighted some emerging problems in this article, focusing on Africa and Nigeria in particular. These problems include a higher risk of coronavirus exposure for body handlers, shortage of cadavers for teaching and learning, a lack of standard regulations leading to unethical body sourcing and handling, and a lack of monitoring and collaboration needed for a well-coordinated Covid-19 pandemic response strategy. If these issues are ignored, the previous gains made in anatomical ethical practices may be destroyed. Some useful recommendations for policymaking geared toward prevention or curtailing these emerging issues have been instilled in this article.     

The Unintentional Effects on Body Donation Programs of a Competency-Based Curriculum in Postgraduate Medical Education

As medical programs place increasing importance on competency-based training and surgical simulations for residents, anatomy laboratories, and body donation programs find themselves in a position of adapting to changing demands. To better assess the demand for “life-like” cadaveric specimens and evaluate the possible impacts that competency-based medical education could have upon the body donation program of McGill University, Canada, the authors tracked, over the course of the last 10 years, the number of soft-embalmed specimens, along with the number of teaching sessions and the residents enrolled in competency-based programs that are using cadaveric material. The results reveal that the number of soft-embalmed specimens used within residency training increased from 5 in 2009 to 35 in 2019, representing an increase from 6% of bodies to 36.5% of the total number of body donors embalmed in this institution. Correspondingly, the number of annual teaching sessions for residents increased from 19 in 2012 to 116 in 2019. These increases in teaching are correlated with increasing number of residents enrolled in competency-based programs over the last 3 years (Pearson r ranging from 0.9705 to 0.9903, and R² ranging from 0.9418 to 0.9808). Those results suggest that the new skill-centered curricula which require residents to perform specific tasks within realistic settings, exhibit a growing demand for “life-like” cadaveric specimens. Institutions’ body donation programs must, therefore, adapt to those greater need for cadaveric specimens, which presents many challenges, ranging from the logistical to the ethical.     

数字内容产品版权保护的演化博弈分析

[目的/意义]基于版权保护的演化博弈分析，有助于探究数字内容产品的原创主体对仿冒行为是否具有容忍度，以及不同仿冒水平下实施版权保护的策略选择，对规范数字内容产品市场主体行为具有一定指导意义。[方法/过程]首先借助演化博弈模型，分析原创主体与仿冒主体的利益演化过程，探究版权保护下原创主体对仿冒水平的容忍行为；然后通过细化博弈双方的利润函数模型，探究原创主体容忍度水平的决定因素。[结果/结论]原创主体对较小的仿冒水平存在一定的容忍度，对较高的仿冒水平零容忍。最大仿冒水平容忍度由仿冒交叉收益系数、收益模型常系数、产品研发成本系数和原创主体的产品研发努力水平倍数4个因素共同决定。     

不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制研究

目的：探讨不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制。方法：将雄性Wistar大鼠50只随机均分为5组：安静对照组（C）、低负荷运动训练组（LT）、中等负荷运动训练组（MT）、高负荷运动训练组（HT）和极高负荷运动训练组（ST），每组10只。各运动组分别进行6周的跑台运动训练。训练方案结束后，取腓肠肌样本，提取线粒体，测定线粒体柠檬酸合成酶（CS）、异柠檬酸脱氢酶（ICD）和α-酮戊二酸脱氢酶（α-KGDHC）活性；线粒体Ga²⁺含量、胞浆NADH、NAD⁺、ATP和ADP含量，以及ICD mRNA转录水平。结果：（1）不同负荷运动训练组线粒体CS、ICD和α-KGDHC的活性均显著高于安静对照组（P < 0.01），且CS和ICD活性由高到低顺序均为：MT组 > HT组 > ST组 > LT组 > C组，α-KGDHC活性由高到低顺序为：HT组 > MT组 > ST组 > LT组 > C组。（2）不同负荷运动训练组线粒体Ca²⁺ 含量均显著高于安静对照组（P < 0.01），其含量由高到低顺序为：MT组 > HT组 > ST组 > LT组 > C组；胞浆NADH/NAD⁺和ATP/ADP的比值均显著低于安静对照组（P < 0.01），其比值由低到高顺序为：MT组 < ST组 < HT组 < LT组 < C组。（3）不同负荷运动训练组ICD mRNA转录水平均高于安静对照组（P < 0.01），其水平由高到低顺序为： MT组 > HT组 > ST组 > LT组 > C组。结论：低负荷、中等负荷、高负荷及极高负荷运动训练均可提高大鼠骨骼肌线粒体三羧酸循环功能，且中等负荷运动训练效果最佳。其机制与胞浆NADH/NAD⁺和ATP/ADP比值、线粒体摄钙能力及限速酶基因的表达有关。     

A Bioethos for Bodies: Respecting a Priceless Resource

The value that willed body donors provide to medical education is priceless. Their precious gift helps to teach anatomy, spatial relationships between morphological structures, anatomical variation, and professionalism to medical students in a way that plastic models, podcasts, and lectures cannot. They are also an important resource for medical research and a wide variety of postgraduate training opportunities. While many body donation programs throughout the world are nonprofit organizations, there are body donation companies in the United States that sell donors for-profit. These “body brokers” have accumulated large profits from this business. It is incongruous that others would profit from such a priceless, freely donated gift. To prevent this incongruity, it is proposed that the international anatomical community develop a normative culture (a bioethos) for body donation programs. This would involve the conscious and systematic development of ethical principles for the day-to-day policies and practices of institutions that collect and use human bodies. With the development of this bioethos, a cultural shift in how donors are treated would occur and, over time, this would become the normal practice. These principles would become fundamental and foundational for the procurement and use of priceless human tissues.     

"以人为本"的大众健美操创编

“以人为本”的大众健美操成套动作的创编不仅要有一定的运动负荷，起到强身健体、减脂和塑造形体的作用，而且要因人而异能够调动人们的积极性，调节人们的情绪，使人们自觉、主动地参加健美操的锻炼。根据创编对象的需要及所要达到的目的不同，动作内容的选择上也应不同。动作组合、结构框架、音乐配备、编排顺序之间要合理，具有新颖、独特的风格与特点，能给人一种美的享受。     

Medieval and renaissance glass technology in Valdelsa (Florence). Part 1: raw materials, sands and non-vitreous finds

A significant number of archaeological finds of the 13th–16th century from the Tuscan sites of Germagnana and Gambassi in Valdelsa—FI, was studied by different physico-chemical investigations (SEM–EDS, ICP, Mössbauer spectroscopy, XRD, XRF, TG-DTA) in order to contribute to clarify the production methodology and the pre-industrial glass manufacture technology. The studied samples are mainly non-vitreous finds as production waste, refractory materials, crucibles and raw materials; also vitreous finds as frits, skims, glasses (glass masses, glass working waste and finished products) have been taken into consideration. The obtained petrographic and physico-chemical data strongly suggest that both Gambassi and Germagnana glass manufactures were strictly connected with the sources of vitrifiable materials, situated in Tuscan sand quarries. In particular a comparison between sands from the neighbouring quarries and appropriate finds of the two archaeological sites evidences that the employed vitrifiable materials possibly belong to La Casina La Cava resort. The archaeological classification, based on macroscopic observation and stratigraphic position, was compared and verified with the scientific classification of the examined finds of Germagnana and Gambassi sites based on their composition, morphology and physico-chemical properties.     

女子大众艺术健身操锻炼效果的实验研究

以 6 0名 18岁以上女子为研究对象 ,采用自编的四套大众艺术健身操 ,每周进行三次练习 ,每次 6 0分钟。持续练习 8周。结果表明 :大众艺术健身操练习可以减小女子身体各部位的围度 ,具有改善女子的形体特征的作用。不仅有非常明显的减肥作用 ,而且具有增加瘦体重从而改变身体成分 ,达到增强体质的作用。对于体重超重和肥胖者 ,减肥和降体重 ,改善身体成分的作用更为显著。大众艺术健身操对提高女子呼吸系统、循环系统机能水平也有一定的作用。对提高女子的力量、灵敏性、平衡能力及反应速度等身体素质有显著的作用。     

关于中国男篮在世界大赛中成绩滑坡的原因剖析

采用文献资料与理论分析等方法 ,对中国男篮在第 2 7届奥运会和第 14届男篮世锦赛上攻、防技术资料进行分析研究 ,发现中国男篮整体实力确有提高 ,尤其是内线实力明显增强。但由于我国对篮球本质认识上的偏差 ,过分追求队员高度而忽视速度、战术与技术训练 ,特别是外线控球能力的培养 ,结果比赛时内、外线脱节 ,整体攻、防节奏慢 ,不仅内线实力难以发挥 ,相反丢失了过去快速、灵活的优势与特点。针对存在的问题 ,从主观认识、训练方法以及训练内容等方面提出了一些建议和改进措施。     

中、日、美、英体育教学发展共同趋向研究

世纪之交,为了适应本国社会发展的需要,中国、日本、美国和英国都在深化体育教学改革。运用比较分析法等研究方法,对中、日、美、英体育教学的发展动向进行了研究。研究发现:中、日、美、英体育教学目标向着健康化、终身化、多元化的方向发展;体育教学内容越来越关注学生身心健康发展和终身体育的需要,体育教学评价更加注重过程性评价和个体评价,评价内容日益多元化。