罗格列酮和有氧运动对糖尿病糖脂代谢紊乱的干预作用

为探讨罗格列酮和运动对糖尿病糖脂代谢紊乱的干预作用,选用3～4周龄NOD小鼠作为实验材料,分别施加罗格列酮和中等强度有氧耐力运动。通过观察小鼠外在表现、体重和腹部脂肪变化以及胰腺病理切片,检测血清胰岛素水平、血液生化指标,显示罗格列酮和有氧运动对糖尿病糖脂代谢紊乱具有良性干预作用。     

绵羊微卫星标记与部分毛用性状的关系研究

根据Genbank在绵羊1、6号染色体上选取了5个微卫星基因座,对待测绵羊群体所有的表型数据资料按基因型分组进行方差分析和多重比较后,得出结论: OarJMP8可以对羊毛自然长度性状进行标记。BM6438和BM6506可以对羊毛细度进行标记。在绵羊六号染色体上的OarJMP8附近存在控制羊毛自然长度的QTLs;在绵羊第1号染色体的BM6438和BM6506区域可能存在控制羊毛细度的QTLs。     

对普通高校短跑训练侧重点的探讨

通过分析世界优秀短跑运动员的百米成绩 ,论述了在短跑训练中应以发展运动员的最高速度作为重点进行突破 ,并从生理学、生物化学及生物力学的角度对其进行了细致地分析 ,对快速提高短跑成绩提出了行之有效的训练方法     

论文学功能系统与特质

传统的作品功能观把本视为学功能的发生源，把读视为学功能作用的被动对象，本提出：学功能必须在具体的学活动中才能产生，学活动是学功能的发生源。学功能联系于学活动的动态开放整体的流程，并对投身于学活动的一切实践主体（作与读）产生系统效能，学功能系统由认知，净化，愉悦，生命四个各具丰富内涵的子系统构成，并通过系统质的审美化合指向人本身，指向人自身的丰富与完善，指向人的诗意人生，因此，学功能是学之人学本义的回归。     

Evaluation of urinary abnormalities in urolithiasis patients: A study from North India

Metabolic abnormalities were investigated in 44 stone patients with first time (group 1) and 56 with 2 times stone formation (group 2), and in 25 normal individuals. 24hr urine was analysed spectrophotometrically for oxalate, calcium, magnesium, citrate, uric acid, phosphate and creatinine. Hypocitraturia and hyperoxaluria were the common abnormalities in the stone formers. Stone patients had significantly higher urinary oxalate, calcium and uric acid and lower phosphate than normal individuals. Citrate/calcium and magnesium/calcium ratio were significantly high in normal individuals than stone formers. Patients in group 2 excreted significantly higher urinary calcium and lower citrate that patients in group 1. Citrate/calcium ratio was higher in group 1 than group 2. Hypocitraturia, hyperoxaluria, hypercalciuria and increased citrate/calcium and magnesium/calcium ratio seem to be an essential risk factor for stone formation. Patients with recurrent stone formation could be distinguished from patients with first time stone formation on the basis of urinary calcium and citrate.     

Understanding divergent domestication traits from the whole-genome sequencing of swamp- and river-buffalo populations

Domesticated buffaloes have been integral to rice-paddy agro-ecosystems for millennia, yet relatively little is known about the buffalo genomics. Here, we sequenced and assembled reference genomes for both swamp and river buffaloes and we re-sequenced 230 individuals (132 swamp buffaloes and 98 river buffaloes) sampled from across Asia and Europe. Beyond the many actionable insights that our study revealed about the domestication, basic physiology and breeding of buffalo, we made the striking discovery that the divergent domestication traits between swamp and river buffaloes can be explained with recent selections of genes on social behavior, digestion metabolism, strengths and milk production.     

企业家人口统计特征对中小企业融资约束的影响机制研究

基于高层梯队理论,以2010年我国530家中小上市企业为样本,采用层级回归方法,分析企业家人口统计特征对中小企业融资约束的影响及其作用机制。研究结果表明,企业家不同的人口统计特征对中小企业融资约束产生不同的影响,具体来说,企业家受教育程度和职称对缓解中小企业融资约束产生积极影响,企业家年龄和任期对中小企业融资约束产生显著的U型影响,而女性企业家对缓解中小企业融资约束产生消极影响。研究结果不仅丰富了企业家人口统计特征与中小企业融资约束之间的相关理论,并为缓解我国中小企业融资约束提供了实践支持。     

Comment on Dissociation between running economy and running performance in elite Kenyan distance runners

Mooses and colleagues suggest that running economy alone does not explain superior distance running performance in elite Kenyan runners. Whilst we agree with the multi-factorial hypothesis for Kenyan running success, we do not believe that running economy can be overlooked to the extent that it was based on this particular study. Based on the methods used and the range of athletes tested, in this response letter we question whether this study provides any basis for downplaying the influence of running economy or suggesting that other factors compensate for it to enable superior performance.     

Effects of interval aerobic training combined with strength exercise on body composition,glycaemic and lipid profile and aerobic capacity of obese rats

The purpose of this study was to investigate the effects of interval aerobic training combined with strength exercise in the same training session on body composition, and glycaemic and lipid profile in obese rats. Sixteen lean Zucker rats and sixteen obese Zucker rats were randomly divided into exercise and sedentary subgroups (4 groups, n = 8). Exercise consisted of interval aerobic training combined with strength exercise in the same training session. The animals trained 60 min/day, 5 days/week for 8 weeks. Body composition, lipid and glycaemic profiles and inflammatory markers were assessed.

Results showed that fat mass was reduced in both lean and obese rats following the exercise training (effect size (95% confidence interval (CI)) = 1.8 (0.5–3.0)). Plasma low-density lipoprotein–cholesterol and fasting glucose were lower in the exercise compared to the sedentary groups (d = 2.0 (0.7–3.2) and 1.8 (0.5–3.0), respectively). Plasma insulin was reduced in exercise compared to sedentary groups (d = 2.1 (0.8–3.4)). Some exercise × phenotype interactions showed that the highest decreases in insulin, homeostatic model assessment-insulin resistance, fasting and postprandial glucose were observed in the obese + exercise group (all, P < 0.01). The findings of this study suggest that interval aerobic training combined with strength exercise would improve body composition, and lipid and glycaemic profiles, especially in obese rats.     

花粉管通道法转基因对小麦主要农艺性状的影响

采用花粉管通道法介导外源耐盐基因SeNHX1导入4个小麦品种（品系）BN-64、YM-34、BM-1和AK-58中,并对转基因D0代的主要农艺性状进行了统计分析.结果表明,与对照相比,转基因D0代植株的种子（D1代）千粒重、株高、穗长、旗叶面积均有所提高;D0代植株与对照组相比,株高差异均达到显著水平,甚至极显著水平;穗长除BM-1差异不显著外,其余受体均达显著水平.叶面积差异均达到显著水平;叶长除YM-34外,其余受体差异均达到极显著水平.叶宽与受体相比均无明显差异.