Mystery of the Toxic Flea Dip: An Interactive Approach to Teaching Aerobic Cellular Respiration

We designed an interrupted case study to teach aerobic cellular respiration to major and nonmajor biology students. The case is based loosely on a real-life incident of rotenone poisoning. It places students in the role of a coroner who must determine the cause of death of the victim. The case is presented to the students in four parts. Each part is followed by discussion questions that the students answer in small groups prior to a classwide discussion. Successive parts of the case provide additional clues to the mystery and help the students focus on the physiological processes involved in aerobic respiration. Students learn the information required to solve the mystery by reading the course textbook prior to class, listening to short lectures interspersed throughout the case, and discussing the case in small groups. The case ends with small group discussions in which the students are given the names and specific molecular targets of other poisons of aerobic respiration and asked to determine which process (i.e., glycolysis, citric acid cycle, or the electron transport chain) the toxin disrupts.     

糖酵解供能真假超量恢复区间的探析

超量恢复规律鲜有成功应用的报道,是理论还是实践出了偏差? 为此,文章将通过对真、假超量恢复区间的研究,初探供实践之用的恢复理论.方法:大鼠147只,随机分21组;造模1周后,游泳训练2周.按36h超量恢复区间连续在训练后即刻、休息36h取样.结果:超量恢复组①心脏:前6×36h区间适应期、正叠加,第7区间极限,8-9区间负叠加过程;②肝脏:前4区间正叠加,第5区间极限,6-9区间负叠加过程;③肾脏:前4区间正叠加,第5区间极限,6-9区间负叠加过程;④糖酵解供能:前4区间正叠加,第5区间极限,6-9区间负叠加过程.结论:①超量恢复区间含正、负叠加过程,即真、假超量恢复区间;②负叠加过程的发展终导致过劳死发生,正、负叠加过程的转折点为生理极限.     

短跑训练原理探析

磷酸尿供能系统是100m跑的生化基础,糖酵解供能系统是400m跑的生化基础。短跑训练必须发展这两个系统的供能能力和耐受乳酸能力,发展绝对速度和速度耐力。     

试论足球运动员的无氧能力及训练

足球运动因大强度、长时间激烈拼抢使能量供应系统变得极为复杂，比赛中无氧供能常起着十分重要的作用。足球运动中无氧供能可分为：高能磷化物系统供能和糖酵解供能。而针对这两种供能形式可分为一般无氧和专项无氧能力训练。     

突破800米成绩障碍的生理学设计

本文对800米跑的特点及其训练手段进行了生理学剖析,提出充分挖掘磷酸原供能潜力,延长糖酵解供能时间,提高有氧代谢供能质量,重视提高产生乳酸的能力、耐受乳酸的能力和消除乳酸的能力,可在短期内突破800米跑成绩的障碍。     

大强度训练对大鼠红细胞糖酵解代谢及2,3-二磷酸甘油酸的影响

以大鼠为实验对象,研究7周大强度跑台训练对大鼠红细胞糖酵解代谢及2,3-二磷酸甘油酸浓度的影响.结果发现:1)7周的大强度训练能够明显提高大鼠红细胞内无氧代谢酶LDH活性及代谢底物葡萄糖的浓度,有利于促进糖酵解代谢;2)大强度训练后的大鼠在一次性运动后,红细胞LDH活性在运动后30 min显著升高,HL浓度在运动后30 min有非常显著性升高,同时伴随葡萄糖浓度的明显下降.3)大强度训练7周的大鼠在一次性大强度运动后24 h,红细胞Pk和葡萄糖均恢复到原有水平,但LDH活性仍处于显著高水平.4)大强度训练7周会造成红细胞内2,3-二磷酸甘油酸浓度显著升高,有利于红细胞向组织释放氧气,但其一次性运动对2,3-二磷酸甘油酸的影响,有待进一步的研究.     

促进武术运动员无氧耐力能力的生化分析及方法研究

运用运动生物化学所揭示的人体运动时能量供应体系的关系，结合武术运动的特点，分析了影响武术基动员的生化因素以及提高无氧耐力能力的生化原则和训练方法，对改进传统的武术训练方法，科学的安排训练有效地提高武术技术水平有较好的参考价值。     

废聚酯醇解产物羟值的分析方法

采用乙酸酐 /吡啶回流法和乙酸酐 /高氯酸 /乙酸乙酯常温酰化法 ,分别测定了废聚醋醇解产物的羟值。结果表明 ,两种方法测定结果均准确可靠。乙酸酐 /吡啶回流法适用于所有的废聚酯醇解产物 ,但操作麻烦、费时。乙酸酐 /高氯酸 /乙酸乙酯常温酰化法用于深度醇解的醇解产物 ,操作简单、快捷     

400m 跑的供能特点及其训练

400m在短跑项目中，是一个较难驾驭的项目，一直是人们研究的焦点之一。400m跑要求运动员既具备良好的速度，又要具备良好的速度耐力，要想找到其中的最佳契合点，让运动员在比赛中获得最好的成绩，教练员必须了解400跑的供能特点和供能方式，然后根据其特点有针对性地安排训练，才能收到理想的训练效果。     

Regulation of metabolic pathways in liver and kidney during experimental diabetes: Effects of antidiabetic compounds

Diabetes has been classified as a disease of glucose overproduction by tissues, mainly liver and glucose underutilization by insulin requiring tissues like liver, adipose and muscle due to lack of insulin. There is, however, glucose over utilization in tissues not dependent on insulin for glucose transport like kidney, nerve and brain. There are serious complications due to this excess glucose in these tissues and their reversal is important for a good metabolic control and normalisation of other parameters. Insulin, trace metals and some plant extracts have been used to see the reversal effects of the complications of diabetes in liver and kidney in experimental diabetes. Almost complete reversal of the metabolic changes has been achieved in the activities of key enzymes of metabolic pathways in liver and kidney and an effective glucose control has been achieved suggesting a combination of therapies in the treatment of metabolic disturbance of the diabetic state.