硅酸盐-盐（硫酸盐）流体不混溶：蒙古南部Mushugai-Khuduk含火成碳酸岩杂岩体矿物中的熔体包裹体研究

Crystalline and melt inclusions were studied in garnet, diopside, potassium feldspar, and sphene from the garnet syenite porphyry of the carbonatite-bearing complex Mushugai-Khuduk, southern Mongolia. Phlogopite, clinopyroxene, albite, potassium feldspar, sphene, wollastonite, magnetite, Ca and Sr sulfates, fluorite, and apatite were identified among the crystalline inclusions. The melt inclusions were homogenized at 1010℃～1080℃ and analyzed on an electron microprobe. Silicate, salt, and combined silicate-salt melt inclusions were found. Silicate melts show considerable variations in SiO2 concentration （56 to 66wt% ）, high Na2O ＋ K20 （up to 17wt% ）, and elevated Zr, F, and Cl contents. In terms of bulk rock chemistry, the silicate melts are alkali syenites. During thermometric experiments, salt melt inclusions quenched into homogeneous glasses of predominantly sulfate compositions containing no more than 1.3wt% SiO2. These melts are enriched in alkalis, Ba, Sr, P, F, and Cl. The investigation of the silicate and salt melt inclusions in minerals of the garnet syenite porphyries indicate that these rocks were formed under influence of the processes of crystallization differentiation and magma separation into immiscible silicate and salt （sulfate）liquids.     

Diagnostic Dilemma of HbA1c Detection in Presence of a Hemoglobinopathy: A Case Report

We report a case of a diabetic, heterozygote with near normal hematology, marginally low level of hemoglobin A₂(HbA₂) having an increased level of hemoglobin F(HbF) that was pancellularly distributed among the red cells. BioRad DiaSTAT measurements gave a high glycated hemoglobin A1c(HbA1c) of 31.5% and the BioRad Variant analyzer recorded an HbA1c value which was very low, in discordance with the detected blood glucose levels. Flow cytometry and polymerization chain reaction (PCR) based studies were carried out which revealed the case to be that of the common hereditary persistence of fetal hemoglobin (HPFH)-3, an Asian Indian mutation. Fructosamine estimation and HbA1c by Boronate affinity chromatography were able to resolve the discordant value detected and was able to confirm the diabetes status. The case would have been a diagnostic dilemma, if reported without correlation.     

新疆萨惹什克锡矿与萨北碱性A型花岗岩成因关系的年代学制约

新疆东准噶尔地区的萨惹什克锡矿呈脉状产于萨北花岗岩体中。对于这种脉状矿床，成岩和成矿近时性的时间制约是证明矿床与围岩有成因关系的首要证据。萨北岩体由含碱性铁镁矿物的碱性花岗岩组成，全岩地球化学结果显示，碱性花岗岩具高碱、低Ca，明显富集稀土元素、高场强元素（zr，Hf，Nb，Ta，Y）和大离子亲石元素（Rb，Th，U），而强烈亏损Sr，Ba，Eu，属于典型的碱性A型花岗岩。锡矿脉由占绝对优势的锡石和石英组成，受北东和近东西向的断裂破碎带控制。原有研究证实，形成该锡矿床的成矿流体属于具高温、低盐度和低密度的岩浆水。据此并结合锡矿体的围岩性质，前人认为锡矿床与碱性花岗岩有成因联系。但是，由于分析技术和样品选择上的制约，萨北岩体成岩和萨惹什克锡矿成矿的确切时代一直没有得到合理的解决。本文报道了我们最近获得的碱性花岗岩锆石IA-ICP-MS U-Pb和锡矿石辉钼矿Re-0s同住素年龄（分别为306±3Ma和307±11Ma）。上述结果表明，萨北碱性花岗岩和萨惹什克锡矿石属于同期地质事件的产物，从而为两者具有密切成因联系提供了重要的年代学制约。此外，根据碱性花岗岩的БNd（t）（=＋5.0）低于研究区亏损地幔4.5个Б单位，我们认为形成萨北岩体的花岗岩浆不是直接来源于亏损地幔玄武质岩浆结晶分异作用的产物，而更可能是起源于本区年轻洋壳和陆源沉积物的部分熔融。     

针剂注射液中亚硫酸钠含量的化学发光测定

亚硫酸钠与酸性的吐温80,罗丹明6G混合溶液相遇产生强烈的光信号,其化学发光强度与亚硫酸钠的浓度在0．05—10μg mL^-1（r=0．998）范围内呈良好的线性关系,方法的检出限为0.03μG mL^-1。并成功应用于针剂注射液中Na2SO3含量的测定。     

Studies on some serum enzyme levels in various liver diseases

Serum alkaline phosphatase (ALP) (EC 3.1.3.1), 5′nucleotidase (5′NT) (EC 3.1.3.5), aldolase (ALD) (EC 4.1.2.13) and sorbitol dehydrogenase (SDH) (EC 1.1.1.14) were estimated in infective hepatitis, alcoholic hepatitis, chronic active hepatitis, obstructive jaundice, cirrhosis of liver and amoebic liver abscess. It was observed that serum ALP and 5′NT were significantly increased in all cases of chronic active hepatitis and obstructive hepatic disease. However, the elevation observed in the latter was much higher than the former. Serum SDH and ALD levels were elevated in all cases of infective hepatitis, studied though increase in the former was much higher than the latter, suggesting its significance in the diagnostic confirmation of this disease. Results presented suggest 5′NT and SDH as more reliable diagnostic test compared to ALP and ALD for obstructive jaundice and infective hepatitis respectively.     

Hospital based preliminary study on osteoporosis in postmenopausal women

The awareness of osteoporosis has grown world wide in recent years. This silently progressing metabolic bone disease is widely prevalent in India, and osteoporotic fractures are a common cause of morbidity and mortality in adult Indian men and women. Rapid bone loss occurs in postmenopausal women due to hormonal factors which lead to increased risk of fractures. Biochemical markers of bone metabolism are used to assess skeletal turnover. A cross-sectional study of 150 pre- and post menopausal women was carried out at S.D.M College of Medical Sciences and Hospital, Dharwad, during the period of May 2005 to September 2005. The study group consisted of 75 Premenopausal women in the age group of 25–45 years and 75 Postmenopausal women in the age group of 46–65 years. Bone formation markers (Total Calcium, lonised calcium, Phosphorus, Alkaline phosphatase), and bone resorption markers (Urinary Hydroxyproline) were analysed in pre and post menopausal women. Bone formation markers, Total and lonised calcium were significantly decreased (p<0.001) and Alkaline phosphatase was significantly increased (p<0.001) in postmenopausal women compared to premenopausal women. Bone resorption markers, Urinary hydroxyproline excretion was significantly increased (p<0.001) in postmenopausal women. The results from this study suggest that simple, easy, common biochemical markers can still be used to assess the bone turnover in postmenopausal women and hence their risk of developing osteoporosis and fractures.     

碳酸氢钠对人体运动能力的影响

通过对三种不同供能形式为主的运动项目运动员服用碳酸氢销后对运动成绩和某些生理生化指标的影响方面的研究进行综述和分析,揭示了服用碳酸氢钠诱导碱中毒对运动能力影响的机制。证实了口服一定剂量的碳酸氢钢有助于提高机体以乳酸能系统供能为主的运动项目的成绩。     

云南永平卓潘新生代碱性杂岩体的元素地球化学和Nd-Sr-Pb同位素特征及地质意义

云南永平卓潘碱性杂岩体是金沙江-哀牢山富碱斑岩带中的重要岩体,位于兰坪走滑拉分盆地西部.该岩体的主要岩石类型为辉石正长岩、正长岩和霞石正长岩等.岩石地球化学显示高碱、高K2O/Na2O比值、低TiO2、高Al2O3的超钾质钾玄岩系列岩石.微量元素表现为富集K、Rb、Sr、Ba等大离子亲石元素（LILE）,亏损Ta、Nb、Ti、P、Zr等高场强元素（HFSE）,表现为明显的“Ta-Nb-Ti”负异常,同时富集过渡性元素Cr、Ni、Co等.稀土元素为稀土总量高,富集LREE、（La/Yb）N比值高、Eu异常不明显为特征.（^87 Sr/^86 Sr）i比值为0.707611～0.709167、εNd（t）值为-4.89～-6.57,206Pb/204Pb变化于18.6886～18.7022、207Pb/204Pb变化于15.6169～15.63493、208Pb/204Pb变化于38.7972～38.8927,显示岩浆源区具有富集地幔（EM Ⅱ）与下地壳共同作用的壳幔过渡带特征,构造环境判别为大陆弧（CAP）环境.岩体是在碰撞造山过程中大陆板片俯冲,使曾经遭受古洋壳板片流体强烈交代的壳幔过渡带在上升的软流圈熔体的注入而发生部分熔融,在走滑拉分盆地的核心部位沿构造断裂上升侵位而形成.     

Serum enzymes in thermal injury

Various metabolic and biological changes follow burn injury. Serum Thio-barbituric acid reactive substances (TBARS), transaminases, alkaline phosphatase and amylase were measured in 43 patients with thermal injury over the first 10 days of post burn period. No clear correlation between elevated serum enzymes except amylase and the burn size was observed on admission. Mean serum TBARS were significantly increased in the burn patients. Transaminases values increased till 5^th day then declined on 10^th day, whereas alkaline phosphatase and amylase activities continued to rise till day 10. It is concluded that functional disturbances occur in liver and pancreas around a week after thermal injury. Monitoring serum ALP and amylase in postburn period has valuable prognostic importance.     

Effect of spironolactone on acid and alkaline phosphatase in the testes of albino rat

The biological activity of the mineralocorticoid antagonist, spironolactone depend upon its metabolism. In this study the effect of diuretic drug compound spironolactone on the acid and alkaline phosphatase in the testes of albino rat. The drug spironolactone was administered orally daily for 7^th, 14^th and 21^st days at the dose of 100 mg/kg body weight. Among them, the side effects of drug are that the degradation of alkaline phosphatase in the testes; while acid phosphatase increased significantly may be due to 7a-thiospironolactone is a tissue metabolite of spironolactone and may contribute to the testicular enzymes, therapeutic actions and some other side effects. It is suggested that the decrease and increase of alkaline and acid phosphatase in the testes of albino rat are the due to the side effects of spironolactone drug compound.