Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.     

Digital Module 05: Diagnostic Measurement—The G‐DINA Framework https://ncme.elevate.commpartners.com

In this ITEMS module, we introduce the generalized deterministic inputs, noisy “and” gate (G‐DINA) model, which is a general framework for specifying, estimating, and evaluating a wide variety of cognitive diagnosis models. The module contains a nontechnical introduction to diagnostic measurement, an introductory overview of the G‐DINA model, as well as common special cases, and a review of model‐data fit evaluation practices within this framework. We use the flexible GDINA R package, which is available for free within the R environment and provides a user‐friendly graphical interface in addition to the code‐driven layer. The digital module also contains videos of worked examples, solutions to data activity questions, curated resources, a glossary, and quizzes with diagnostic feedback.     

帆板实际航行中运动学参数的测定

对帆板运动进行三维解析即可有效地分析运动员的操作技能，也可利用测定的运动学参数反过来计算与检验空气动力学参数与水动力学参数。介绍了帆板运动的运动学参数、测定的方法。分析了帆板运动学参数测试的可行性。     

园林景观动画设计初探

本文通过对计算机三维动画的相关理论与技术的初步探讨，并结合环境景观动画的制作实例，介绍了该技术在园林景观动画设计方面的应用和发展前景。     

中国北方汉族青年ACE 基因I/ D多态性频率分布特征

通过分析与探讨汉族普通人群ACE基因I／D多态频率分布特征，试图为中国优秀耐力运动员的基因选材研究提供中国人相关人群ACE基因I／D多态频率分布的基础数据。选择18-22岁汉族学生216名作为研究对象，观察其ACE基因I／D多态频率分布。结果显示：北方汉族青年的ACE基因I／D多态频率分布，与国内相关研究结果一致，与欧美人群有非常显著差异。研究认为：从种族单一性、样本数量和年龄段的选择等因素考虑．研究结果不仅可以作为北方汉族青年ACE基因I／D多态频率分布的代表，而且对于杰出耐力的多态性标记研究来讲是理想的对照群体。     

第16届世界杯足球赛亚洲球队与世界杯前八名球队运用定位球进攻战术之比较

为了提高我国高层次足球队定位球进攻战术水平，通过对第16届世界杯决赛阶段亚洲球队和世界杯前八名球队定位球进攻情况的调查统计、对比研究，初步分析了世界强队的优势及亚洲球队普遍存在的问题。研究表明，亚洲球队有意识、有目的地制造和利用定位球战机的能力差；上半时运用次数少，且质量低，效果差；在运用不同的定位球进攻方式中，角球进攻破门得分的水平与世界强队的差距较大。     

三维模型库的参数化建模

文章探讨了用SolidEdge软件参数化快速建模,从而大大加快了建立三维模型库的速度,三维模型库可用于多媒体教学.     

国家队专项器材管理系统的研制与应用

为提高国家队专项器材管理效率,依据<国家队专项器材暂行管理办法>,在调研建立国家队专项器材配置标准基础上,利用COM 组件技术,开发研制了"国家队专项器材管理系统"软件,该软件在2004年的试用、2005年的全面推广应用中,取得了较好的效果,基本满足了国家体育总局经济司、16个运动项目管理中心、财务结算和审计中心、体育器材装备中心等部门在国家队专项器材预算、计划、审批、购置等方面的信息化工作需求,首次尝试性实现了国家体育总局系统内基于因特网技术的一站式服务,创新性地实现了多角色同步操作和管理者的实时监控工作局面,有力支持了国家队备战北京奥运会的保障工作.     

NBA2004-2005赛季总决赛攻防特征分析

文章分析了NBA04-05赛季总决赛两支球队的攻防特征,阐述了马刺队获胜的主要原因在于战术上进攻路线变幻大,并极大限度地发挥了三分球的优势,防守上成功遏制住了对方主力的进攻火力.这些对于我国CBA或国家队的发展具有很大的启发意义.     

八点算法的降维EVD技术

传统的应用于双视图三维复原的八点算法使用标准特征值分析(EVD)算法。通过统计分析可知,该技术存在估计偏差大和均方误差都大的缺点。其产生原因是数据噪声的有色性和自相关函数矩阵的条件数过大,因此白化数据噪声和正则化变换是提高性能的有效措施。通过理论分析和计算机仿真实验,表明文中所给出的降维EVD技术固有地同时具备噪声预白化功能和数据正则化功能,因此它能给出均方误差相当小的无偏估计。由于它无须进行预白化变换或正则化变换,并把最优化过程的维数从9降为4,所以它还具有计算快速、实现简单方便的优点。