A fluid collection system for dermal wounds in clinical investigations |
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| Authors: | Michael Klopfer Derek Banyard G.-P. Li Alan Widgerow Mark Bachman |
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| Affiliation: | 1.Department of Biomedical Engineering, Henry Samuelli School of Engineering, University of California at Irvine, Irvine, California 92697, USA;2.Department of Plastic Surgery, Center for Tissue Engineering, School of Medicine, University of California at Irvine, Orange, California 92868, USA |
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| Abstract: | In this work, we demonstrate the use of a thin, self adherent, and clinically durable patch device that can collect fluid from a wound site for analysis. This device is manufactured from laminated silicone layers using a novel all-silicone double-molding process. In vitro studies for flow and delivery were followed by a clinical demonstration for exudate collection efficiency from a clinically presented partial thickness burn. The demonstrated utility of this device lends itself for use as a research implement used to clinically sample wound exudate for analysis. This device can serve as a platform for future integration of wearable technology into wound monitoring and care. The demonstrated fabrication method can be used for devices requiring thin membrane construction. |
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