| 右旋布洛芬缓释胶囊的释放度考察 |
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| 引用本文： | 杨成雄,赵平华.右旋布洛芬缓释胶囊的释放度考察[J].荆门职业技术学院学报,2009,24(2):39-42. |
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| 作者姓名： | 杨成雄 赵平华 |
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| 作者单位： | 杨成雄,YANG Cheng-xiong(荆楚理工学院化工与药学院,湖北,荆门,448000);赵平华,ZHAO Ping-hua(荆门市药品检验所,湖北,荆门,448000)
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| 摘 要： | 目的：考察右旋布洛芬缓释胶囊的释放度。方法：采用转篮法，溶出介质为pH6．0的磷酸盐缓冲液，对研制的右旋布洛芬缓释胶囊的三批样品的释放均一性和辅料、胶囊以及滤膜对释药的影响进行考察。结果：三批样品的各时段取样点的释放度相差不大，均匀度较好，均在规定的范围内；辅料、胶囊和滤膜对释药试验的结果没有干扰。结论：研制右旋布洛芬缓释胶囊释药稳定，其释放度测定法可以作为其质量控制的方法。
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| 关 键 词： | 盐酸曲马多 口腔崩解片 溶出度 均匀度 质量控制 |
The Delivery Test of Modified Release Capsule of Dex-ibuprofen |
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| YANG Cheng-xiong,ZHAO Ping-hua.The Delivery Test of Modified Release Capsule of Dex-ibuprofen[J].Journal of Jingmen Vocational Technical College,2009,24(2):39-42. |
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| Authors: | YANG Cheng-xiong ZHAO Ping-hua |
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| Institution: | 1 Jingchu University of Technology;Jingmen;Hubei;448000;China;2 The Institute of Medicines Inspection of Jingmen;China |
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| Abstract: | Objective:The delivery test of modified release capsule of Dex-ibuprofen.Methods:The delivery test of modified release capsule of Dex-ibuprofen had been done in buffer phosphate(pH6.0) by rolling basket,and investigate the effect by adjuvant,capsule and filter membrane to modified release capsule of Dex-ibuprofen.Results:The delivery test of modified release capsule of Dex-ibuprofen had no difference in three group samples and was not been able to change by adjuvant,capsule and filter membrane.Conclusion:Th... |
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| Keywords: | Dex-ibuprofen modified release capsule the delivery test |
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