| 能量限制与有氧运动对小鼠脂肪组织ZAGmRNA表达的影响 |
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| 引用本文： | 李薇薇,袁海平,刘琼. 能量限制与有氧运动对小鼠脂肪组织ZAGmRNA表达的影响[J]. 上海体育学院学报, 2011, 0(5) |
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| 作者姓名： | 李薇薇 袁海平 刘琼 |
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| 作者单位： | 上海体育学院运动科学学院; |
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| 基金项目： | 上海市重点学科(第3期)建设资助项目(S30802); 上海体育学院研究生创新基金资助项目(YJSCX2009S34) |
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| 摘 要： | 目的:观察能量限制与有氧运动对小鼠脂肪组织ZAGmRNA表达的影响。方法:将雄性昆明小鼠(48只)随机分为对照组(C)、限能组(CR)、有氧运动组(AE)、限能+有氧运动组(CR+AE),每组12只;干预8周后测定各组小鼠的体重增加值、腹腔脂肪垫重量、血清TG、TC、LDL-C、HDL-C含量;采用实时荧光定量PCR法检测小鼠脂肪组织ZAGmRNA表达水平。结果:CR组、AE组、CR+AE组的体重增加值、腹腔脂肪垫相对重量,血清TG、TC、LDL-C含量显著低于C组,而血清HDL-C含量及脂肪组织ZAGmRNA表达水平显著高于C组(P<0.05,P<0.01);CR+AE组的脂肪组织ZAGmRNA表达水平显著高于CR组和AE组(P<0.01);脂肪组织ZAGmRNA的表达水平与体重增加值、腹腔脂肪垫相对重量、血清TG、TC含量呈显著负相关(P<0.01)。结论:合理的能量限制与有氧运动能上调小鼠脂肪组织ZAGmRNA的表达,减少内脏脂肪量,降低血脂,减轻小鼠体重。
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| 关 键 词： | 小鼠 肥胖 能量限制 有氧运动 ZAG 脂肪组织 |
Effects of Calorie Restriction and Aerobic Exercise on the Expression of ZAGmRNA in Adipose Tissue of Mice |
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| LI Wei-wei,YUAN Hai-ping,LIU Qiong School of Kinesiology,Shanghai University of Sport,Shanghai ,China. Effects of Calorie Restriction and Aerobic Exercise on the Expression of ZAGmRNA in Adipose Tissue of Mice[J]. Journal of Shanghai Physical Education Institute, 2011, 0(5) |
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| Authors: | LI Wei-wei YUAN Hai-ping LIU Qiong School of Kinesiology Shanghai University of Sport Shanghai China |
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| Affiliation: | LI Wei-wei,YUAN Hai-ping,LIU Qiong School of Kinesiology,Shanghai University of Sport,Shanghai 200438,China |
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| Abstract: | The study tries to probe into the effects of calorie restriction and aerobic exercise on the expression of ZAGmRNA in adipose tissue of mice.Forty-eight KM male mice were randomly divided into 4 groups;control(C,n = 12),calorie restriction group(CR,n = 12),aerobic exercise group(AE,n = 12 ), calorie restriction + aerobic exercise group(CR + AE,n = 12). The experiment lasted for 8 weeks and the weight gain,the relative weight of visceral fat,the serum level of TG,TC,LDL-C,HDLC were measured.The results show ... |
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| Keywords: | mice obesity calorie restriction aerobic exercise ZAG adipose tissue |
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