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Bcl-2、Bax及Bid与细胞周期阻滞及凋亡调控的关系
引用本文:王文文,邓毛程.Bcl-2、Bax及Bid与细胞周期阻滞及凋亡调控的关系[J].广东轻工职业技术学院学报,2009,8(3):21-24.
作者姓名:王文文  邓毛程
作者单位:广东轻工职业技术学院食品与生物工程系,广东,广州,510300
摘    要:Bcl-2家族是研究的最早与凋亡相关的因子,发挥抗凋亡或促凋亡的作用,是线粒体凋亡通路中最主要的调节因子。近年来对于Bcl-2家族的研究取得了很大的进展,个别Bcl-2家族成员不仅具有凋亡调节作用,与细胞增殖也密切相关,从而将细胞周期与细胞凋亡偶连。本文较全面地综述了Bcl-2家族中Bcl-2、Bax及Bid三个成员与细胞周期关系的研究新进展。

关 键 词:Bcl-2  Bax  Bid  细胞周期  细胞凋亡

The Relationship between Bcl-2,Bax,Bid and Cell Cycle Arrest and Apoptosis Regulation
Wang Wenwen,Deng Maocheng.The Relationship between Bcl-2,Bax,Bid and Cell Cycle Arrest and Apoptosis Regulation[J].Journal of Guangdong Industry Technical College,2009,8(3):21-24.
Authors:Wang Wenwen  Deng Maocheng
Institution:Wang Wenwen,Deng Maocheng(Department of Food Bioengineering,Guangdong Industry Technical College,Guangzhou 510300,China)
Abstract:Bcl-2 family is the earliest factors that studied apoptosis-related.The role of Bcl-2 family members are anti-apoptosis or pro-apoptosis.Bcl-2 family members are important mitochondrial molecules regulating many aspects of mitochondrial physiology.Recently,the researches on Bcl-2 family had made great progress.Interestingly,some Bcl-2 family members not only play a role in cell apoptosis but also regulate cell cycle,so they couple apoptosis and cell cycle control in unique ways.The review is exactly to summ...
Keywords:Bcl-2  Bax  Bid
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