| 瑞香狼毒的化学成分 |
| |
| 引用本文： | 陈健勇,;刘光明,;张于,;郝小江,;何红平.瑞香狼毒的化学成分[J].大理师专学报,2014(8):1-3. |
| |
| 作者姓名： | 陈健勇 ;刘光明 ;张于 ;郝小江 ;何红平 |
| |
| 作者单位： | [1]大理学院药学与化学学院,云南大理671000; [2]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明650201; [3]云南中医学院药学院,昆明650500 |
| |
| 基金项目： | 云南省中青年学术技术带头人后备人才资助项目（2010CI047） |
| |
| 摘 要： | 目的：对瑞香狼毒（Stellera chamaejasme）的化学成分进行研究。方法：采用硅胶柱层析、C18反相柱层析、Sephadex LH-20凝胶柱层析和HPLC等方法分离瑞香狼毒的化学成分,采用波谱技术鉴定化合物的结构。结果：从中共分离鉴定了5个化合物,分别是：（2R,3S）-3-（3,4-二甲氧基苄基）-2-（3,4-亚甲二氧基苄基）丁内酯（1）、haplomyrfolin（2）、双氢芝麻素（3）、异新狼毒素A（4）和瑞香狼毒素B（5）。结论：化合物1~3为首次从该植物中分离得到。
|
| 关 键 词： | 瑞香狼毒 瑞香科 化学成分 |
Chemical Constituents of Stellera chamaejasme |
| |
| Institution: | CHEN Jianyong, LIU Guangming, ZHANG Yu, HAO Xiaojiang, HE Hongping (1.College of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China; 2. State Key Laboratory of Phytochemistry and Plant Resources Sustainable Utilization in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;3. School of Pharmacy, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China) |
| |
| Abstract: | Objective： To research the chemical constituents of Stellera chamaejasme. Methods： The constituents were isolated from the plant by silica gel column chromatography, C18 reversed phase chromatography, Sephadex LH-20 gel filtration chromatography and HPLC. Their structures were elucidated by spectroscopic methods. Results： Five known compounds were isolated and identified as（2R, 3S）- 3-（3, 4- dimethoxybenzyl）- 2-（3, 4- methylenedioxybenzyl）- butyrolactone（1）, haplomyrfolin（2）, dihydrosesamin（3）,isoneochamaejasmine A（4） and ruixianglangdusu B（5）, respectively. Conclusion： Compounds 1-3 were isolated from this plant for the first time. |
| |
| Keywords: | Stellera chamaejasme thymelaeaceae chemical constituents |
| 本文献已被 维普 等数据库收录！ |
|
