Reduced glutathione: Importance of specimen collection |
| |
Authors: | Sarita Chavan Laxmayya Sava Vishal Saxena Sandhya Pillai Alka Sontakke Digamber Ingole |
| |
Institution: | (1) Department of Biochemistry, Pad. Dr. D. Y. Patil Medical College, Pimpri, 4110018 Pune |
| |
Abstract: | Glutathione, the dominant intracellular thiol, plays an important protective role against oxidative stress. The accidental
findings of increased reduced glutathione level postprandially as compared to post absorptive level prompted the design of
present study. Reduced Glutathione levels were estimated in 50 healthy individuals in post absorptive and postprandial phase
by taking whole blood in ACD bulb. Mean postprandial reduced Glutathione (9.60±3.39 μmole/gm of Hb) is significantly increased
than mean postabsorptive level (5.53±0.88 μmole/gm of Hb; p<0.001). It also shows positive correlation (r=0.65) between these
two GSH levels. So present study suggests that post absorptive specimen collection is preferable over random or postprandial
as the former reflects the true basal level of reduced glutathione. |
| |
Keywords: | Reduced Glutathione Non enzymatic Antioxidant |
本文献已被 SpringerLink 等数据库收录! |