| 免疫荧光法检测扁平苔藓特异性抗原的研究 |
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| 引用本文： | 黄东辉,靳培英.免疫荧光法检测扁平苔藓特异性抗原的研究[J].宜春学院学报,2003,25(2):97-98. |
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| 作者姓名： | 黄东辉 靳培英 |
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| 作者单位： | 1. 江门市皮肤医院,广东,江门,529000
2. 中国医学科学院皮肤病研究所,江苏,南京,210042 |
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| 摘 要： | 目的：为了证实扁平苔藓特异性抗原的存在．方法：作者对35例扁平苔藓(LP)进行间接免疫荧光(IIF)研究．结果：发现77．14％的病例在皮损处的颓粒层、棘细胞上层显示荧光沉积，但对照组14种其它皮肤病的30例病人也有46．7％的病例在同样部位显示荧光沉积．4例LP特异性抗原(LPSA)阳性的病人治疗前后分别做IIF法检查其结果均为阳性.结论：对以上结果分析，作者认为用IFF法检查不能证实LP有特异性抗原的存在，而所谓的“LPSA”也不能反映病情的变化．
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| 关 键 词： | 扁平苔藓 扁平苔藓特异性抗原 间接免疫荧光法 |
| 文章编号： | 1671-380X(2003)02-0097-02 |
| 修稿时间： | 2003年2月11日 |
The Study on the Lichen Planus Specific antigen by indirect immunofluorescence |
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| HUANG Dong-hui,JIN Pei-Yin.The Study on the Lichen Planus Specific antigen by indirect immunofluorescence[J].Journal of Yichun University,2003,25(2):97-98. |
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| Authors: | HUANG Dong-hui JIN Pei-Yin |
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| Abstract: | objective: in order to demonstrated the lichen planus specific antigen (LPSA). methods: indirect immunofluorescence (IIF)was used in 35 Lichen Planus (LP) patients. Results: It showed 77.14% of them having specific immunofluorescence staining in stratum granulosum and upper stratum spinosum. Nevertheless, 46.7% of controls with other dermatoses had same staining in the same sites. IIF showed no different finding in 4 LP patients before and after treatment. conclusion: We suggested that no LPSA were able to be confirmed and so called LPSA could not prove useful in reflecting the changes of disease status. |
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| Keywords: | Lichen planus Lichen planus specific antigen Indirect immunofluorescence |
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