| 氟啶草酮合成工艺路线的选择 |
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| 引用本文： | 濮文均,孙均燕. 氟啶草酮合成工艺路线的选择[J]. 南通职业大学学报, 2013, 0(4): 99-102 |
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| 作者姓名： | 濮文均 孙均燕 |
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| 作者单位： | 迈克斯如东化工有限公司,江苏如东226407 |
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| 摘 要： | 对文献报道的氟啶草酮原药合成工艺路线进行了概述，并经实验研究，设计了一条以间三氟甲基苯乙腈为原料的氟啶草酮合成工艺路线，其氟啶草酮总收率达70％以上，含量达99．0％以上，该路线工艺安全、易于工业化。
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| 关 键 词： | 氟啶草酮 合成工工艺路线 选择 |
Route Choice of Fluridone Synthesis |
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| PU Wen-jun,SUN Jun-yan. Route Choice of Fluridone Synthesis[J]. Journal of Nantong Vocational College, 2013, 0(4): 99-102 |
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| Authors: | PU Wen-jun SUN Jun-yan |
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| Affiliation: | (Michaels (Rudong) Chemical Co.,Ltd., Rudong 226407, China) |
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| Abstract: | With the fluridone original drug synthesis route reported in the documents, which was summarized in this paper, the author designed an inter trifluoromethyl phenylacetonitrile as raw fluridone synthesis route through experimental research. Simulation results show that fluridone total yield reached more than 70%, with the content arriving at 99.0% or more. The route process is safe and easy to industrialize. |
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| Keywords: | fluridone synthesis route choice |
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