|
|||||
|
|
Imbalanced expression of mitogen-activated protein kinase phosphatase-1 and phosphorylated extracellular signal-regulated kinases in lung squamous cell carcinoma |
|
| Authors: | Wang Kai Zhang Min Qian Ying-ying Ding Zhe-yuan Lv Jun-hui Shen Hua-hao |
| Institution: | Department of Respiratory Medicine, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. |
| Abstract: | ObjectiveMitogen-activated protein kinases (MAPKs) are correlated with a more malignant phenotype in many cancers. This study was designed to evaluate the predictive value of the expression of MAPK phosphatase-1 (MKP-1) and phosphorylated extracellular signal-regulated kinase 1/2 (p-ERK1/2), as the key regulatory mechanism of the MAPKs, in lung squamous cell carcinoma (SCC). |
| Keywords: | Mitogen-activated protein kinase phosphatase-1 (MKP-1) Extracellular signal-regulated kinase (ERK) Lung squamous cell carcinoma (SCC) Prognostic factor |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |