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| 急性力竭运动对大鼠肝细胞损伤的影响 | |
| 引用本文： | 李善妮,夏君玫,王瑜娟. 急性力竭运动对大鼠肝细胞损伤的影响[J]. 武汉体育学院学报, 2006, 40(1): 61-65 |
| 作者姓名： | 李善妮 夏君玫 王瑜娟 |
| 作者单位： | 1. 湘雅医学院,生物学院生物化学系,湖南,长沙,410083 2. 中南大学,体育教研部,湖南,长沙,410083 3. 湖南财经高等专科学校,体育教学部,湖南,长沙,410083 |
| 基金项目： | 浙江省湖州市自然科学基金 |
| 摘 要： | 研究证明，在发育、稳态、疾病等的生理病理过程中，肝细胞会发生凋亡。通过不同强度力竭运动对大鼠肝细胞损伤的影响，以及氧自由基和线粒体摄取Ca^2＋在肝细胞损伤中所起的作用，探寻力竭运动导致肝细胞损伤的机理。 |
| 关 键 词： | 运动医学 肝细胞 损伤 自由基 线粒体 钙离子 |
| 文章编号： | 1000-520X（2006）00-0061-05 |
| 收稿时间： | 2005-09-02 |
| 修稿时间： | 2005-09-022005-10-29 |
Effects of acute exercises to exhaustion on liver injury in rat |
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| LI Shan-ni,XIA Jun-mei,WANG Yu-juan. Effects of acute exercises to exhaustion on liver injury in rat[J]. Journal of Wuhan Institute of Physical Education, 2006, 40(1): 61-65 | |
| Authors: | LI Shan-ni XIA Jun-mei WANG Yu-juan |
| Affiliation: | 1. Biological Chemistry Dept. ,Xiangya Medical School, Changsha 410083;2. Teaching and Research Office of P. E. ,Southern Univ. , Changsha 410083, China ;3. P.E. Teaching and Research Office of Hunan Finance and Economics Technological School, Changsha 410083, China |
| Abstract: | Many studies have proven that liver cells undergo apoptosis under a broad range of physiological conditions,such as development, homeostasis, diseases and exercises. However, the mechanism of this phenomenon is not clear. This paper, through the influences of different exhaustive exercises on hepatic apoptosis and injury as well as the role oxygen free radicals and mitochondria uptaking calcium play in hepatic injury and apoptosis,attempts to seek the correlation between hepatic injury and apoptosis and exhaustive exerclse. |
| Keywords: | sports medicine liver cell inj ury oxygen free radical mitochondrial calcium |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |