运动性低血色素大鼠血清铁及组织铁变化规律的研究

为了探寻运动性低血色素时大鼠血清铁与组织铁变化的规律,以大鼠为实验对象,采用跑台作为运动方式,建立运动性低血色素大鼠模型,并对其血清、各组织中铁进行测定.实验结果表明:长时间跑台运动导致的运动性低血色素大鼠的铁分布呈现不同的变化趋势.血清铁和骨髓铁--功能铁明显下降;作为贮备铁的重要器官--肝脏铁含量明显升高,而另一重要的贮备铁器官--脾脏中铁含量无显著性改变;肌肉中铁含量明显升高,心脏和脑组织中铁含量无显著性改变.这种变化显示运动性低血色素发展到此阶段时铁代谢的变化规律并具有组织特点,而随着运动性低血色素的进一步发展铁代谢会发生怎样的变化有待于今后进一步的研究.血清铁与骨髓铁的变化呈现较高的正相关,提示血清铁水平可以反映骨髓铁的状况.

Research on the Change Regulations of Serum and Tissue Iron in the Context of Sports Hypochrosis Emergence

In order to explore the change regulations of serum and tissue iron in the context of sports hypochrosis emer- gence, adopted the rats as the research subject and taken the running as the sports mode, the experiment established ani- mal model of sports hypochrosis and investigated the character of iron metabolism and some indexes that reflecting iron me- tabolism when sports hypochrosis happened. The results of the experiment indicate that long-time running lead to that serum iron and tissue iron distribution had different changes such as serum iron and bone marrow iron significantly decreased, liv- er iron and muscle iron significantly increased. Brain iron, spleen and cardiac muscle iron had no obvious changes. These were possibly characteristic changes when sports hypochrosis happens. Serum iron has close relationship with bone marrow iron and serum iron could reflect the level of bone marrow iron.