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前列腺癌预后相关分子标志物
引用本文:张年凤,吴新刚,李光.前列腺癌预后相关分子标志物[J].岳阳职业技术学院学报,2012,27(2):102-105.
作者姓名:张年凤  吴新刚  李光
作者单位:1. 岳阳职业技术学院医学基础部,湖南岳阳,414000
2. 中南大学湘雅附二医院脊柱外科,湖南长沙,410000
摘    要:前列腺癌作为男性生殖系统好发的恶性肿瘤,其发生及预后的判断直接关系到男性的生存健康。传统的前列腺癌预后评价指标,如TNM分期、Gleason评分和PSA表达水平等,对临床预后判断有一定意义。但近些年大量分子标志物的发现和应用为前列腺癌的预后评估提供了更可靠、更准确的依据。文章对与前列腺癌发生、转移及血管生成等相关的分子标志物作一综述。

关 键 词:前列腺癌  预后评估  分子标志物

Prostate Cancer Prognostic Molecular Markers
ZHANG Nian-feng,WU Xin-gang,LI Guang.Prostate Cancer Prognostic Molecular Markers[J].Yueyang Vocational Technical College,2012,27(2):102-105.
Authors:ZHANG Nian-feng  WU Xin-gang  LI Guang
Institution:1.Department of Basic Medical,Yueyang Vocational and Technical College,Yueyang,Hunan 414000; 2.Spine Surgery Department,the Second Hospital of Xiangya Medical College,Central South University,Changsha,Hunan 410000)
Abstract:Prostate cancer is the male reproductive system usual malignant tumor,the occurrence and prognosis is directly related to the male survival and health.The traditional prostate cancer prognosis evaluation indicators,such as TNM stage,Gleason score and PSA expression levels,have some significance in clinical.But in recent years,the discovery and application of many molecular markers for prostate cancer prognosis assessment provides more reliable,more accurate basis.Now the occurrence,metastasis and angiogenesis related molecular markers of prostate cancer are reviewed in this paper.
Keywords:Prostate cancer  prognostic evaluation  molecular markers
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