Estimation of reference values in liver function test in health plan individuals of an urban south Indian population |
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Authors: | Sultana Furruqh D Anitha T Venkatesh |
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Institution: | (1) Department of Clinical Biochemistry, St. John's Medical College, Hospital, 560 034 Bangalore, India |
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Abstract: | Reference intervals in clinical chemistry are commonly based on results of measurements in reference western population or
are taken from the western literature. Reference Values are thought to aid physicians to interpret results of measurements
and, should be representative of a defined group of individuals. This group should be as similar as possible to the patients
under investigation. The reference population in this, study has been recruited from the individuals attending the Health
Plan Clinic who fulfill the defined inclusion and exclusion criteria as well as defined partition criteria. The samples were
sorted based on the decision by the physician. The emerging group of individuals was considered as a reference population
for the hospital patients and the results of measurements in this study was evaluated statistically, to stress on the urgent
need to establish the in-house reference values. The reference limits are defined as the central 95 percentile of the population
after eliminating the outliers. The lower, reference limit is the 2.5 percentile while the upper reference limit constituted
the 97.5 percentile for the population. |
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Keywords: | Reference Intervals Age Gender Reference Population |
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