| 对甲基苯磺酸催化合成2-乙酰氧基苯甲酸 |
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| 引用本文： | 孔祥文.对甲基苯磺酸催化合成2-乙酰氧基苯甲酸[J].实验技术与管理,2011,28(11):30-31. |
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| 作者姓名： | 孔祥文 |
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| 作者单位： | 沈阳化工大学应用化学学院,辽宁沈阳,110142 |
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| 基金项目： | 辽宁省教育科学“十一五”规划立项课题高校精品课程建设的理论与实践研究(JG09DB112); 辽宁省教育厅高等学校科学研究项目计划(202092009) |
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| 摘 要： | 研究了以乙酸酐和2-羟基苯甲酸为原料,以对甲基苯磺酸为催化剂合成2-乙酰氧基苯甲酸的清洁合成工艺,考察了影响合成反应的诸多因素。最佳工艺条件是:物质的量n的比为n(2-羟基苯甲酸)∶n(乙酸酐)∶n(对甲基苯磺酸)=1.0∶2.0∶0.025,反应温度为80～85℃,反应时间为60min,2-乙酰氧基苯甲酸的收率为88.35%。该工艺具有原料价廉易得、不腐蚀设备和无环境污染等优点,可实现清洁化生产。
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| 关 键 词： | 2-乙酰氧基苯甲酸 酯化反应 对甲基苯磺酸 |
Synthesis of 2-acetoxy benzoic acid catalyzed by p-methylbenzenesulfonic acid |
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| Kong Xiangwen.Synthesis of 2-acetoxy benzoic acid catalyzed by p-methylbenzenesulfonic acid[J].Experimental Technology and Management,2011,28(11):30-31. |
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| Authors: | Kong Xiangwen |
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| Institution: | Kong Xiangwen (Applied Chemistry College,Shenyang University of Chemical Technology,Shenyang 110142,China) |
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| Abstract: | A cleaner synthesis of 2-acetoxy benzoic acid by the esterification of 2-hydroxy benzoic acid and acetic anhydride using p-methylbenzenesulfonic acid as catalyst was reported.The influences of some factors on the synthesis process were studied.The optimal reaction conditions were chosen that the molar ratio of 2-hydroxy benzoic acid and acetic anhydride and p-methylbenzenesulfonic acid was 1.0∶2.0∶0.025,reaction temperature was 80～85 ℃,reaction time was 60 min,etc.The yield reached 88.35%.After adopting the new process which had many advantages,such as easy preparation,low cost,non-corrosive to equipment,and pollution-free to environment,the production of 2-acetoxy benzoic acid was carried out under cleaning. |
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| Keywords: | 2-acetoxy benzoic acid esterification p-methylbenzenesulfonic acid |
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