| 感冒通对小白鼠的毒性研究 |
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| 引用本文： | 金乐群,穆金秀,吴健翎,王玉珍,王淑强,左东升. 感冒通对小白鼠的毒性研究[J]. 河北北方学院学报(医学版), 1994, 0(2) |
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| 作者姓名： | 金乐群 穆金秀 吴健翎 王玉珍 王淑强 左东升 |
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| 作者单位： | 药理教研室(金乐群，穆金秀)，一附院检验科生化室(吴健翎)，病理教研室(王玉珍，王淑强)，病理教研室(左东升) |
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| 摘 要： | 给不同年龄组小白鼠以不同剂量感冒通灌胃,小白鼠存活率下降,体重减轻,肝脏、肾脏的相对重量增加,胸腺相对重量减少。病理组织学观察结果表明:感冒通对小白鼠肝、肾等脏器有不同程度的损伤,且鼠龄愈小,用药剂量愈大,损伤愈重。
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| 关 键 词： | 感冒通 毒理学 小白鼠 |
TOXICOLOGIC STUDY OF COMPOUND DICLOFENAC SODIUM IN MICE |
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| Jin Le-Qun et al. TOXICOLOGIC STUDY OF COMPOUND DICLOFENAC SODIUM IN MICE[J]. Journal of Hebei North University:Medical Edition, 1994, 0(2) |
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| Authors: | Jin Le-Qun et al |
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| Affiliation: | Jin Le-Qun et al |
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| Abstract: | In our experiment, the different age mice were given diff- erent doses of compound diclofenac sodium(CDS)ig.and the toxicologic effects were observed.All the results implied that the changes induced with CDS, including the reduction of survival rate, the decrease in body weight, the increase in weight of lver and kidney,were related to the doses.The mor-phological study showed that CDS could induce the impairment of liver and kidney, and the younger the mice were and the larger the dose of CDS was, the more sevre the impairment was. |
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| Keywords: | Diclofenac 9odium Toxicology mouse |
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