体外受精多倍体受精卵生成影响因素分析

为了解全外受精（ＩＶＦ）多倍体受精卵生成的影响因素，探索降低该类异常受精的途径，用卡方检验考察１４５个周期ＩＶＦ的多倍体受施放经与夫妇年龄、促排卵方案、穿刺卵光数、获取卵细胞数、授精前孵育时间、精液精子和授精精子的质量和数量的关系，得知成熟卵多倍体受精卵生成率，在刺卵泡烽较多时显著性下降，未成熟卵多倍体受精卵生成率，在精液高活力精子或授精精子交高时显著性上升，结果表明成熟卵和未成熟卵的多倍体受精卵

Analyses of Factors Affecting the Occurrence of Polyploid Embryos in In-vitro Fertilization

To investigate the affecting factors on the occurrence of polyploid embryos in in vitro fertilization (IVF), the relationship of the incidences of polyploid embryos in matured and immatured oocytes and some factors in 145 cycles of IVF were examined respectively. The results show that the ages of the couple, the stimulating protocol, the number of obtained oocytes and the preinsemination interval have no significant influences on the incidence of polyploid embryos. However, this incidence in matured oocyte is significantly reduced when the number of the punctured follicles exceeds 15, while in immatured oocyte, it is significantly increased when the densities of grade II and III of seminal sperms or inseminational sperm are at relatively higher levels. These results suggest that the formation machinism of polyploid embryos in matured and immatured oocytes might be different and it will be of benefit to stimulate greater number of follicles and control the amount of inseminational sperm for immatured oocytes, especially in the case with a higher level of motile sperm so as to diminish the incidence of polyploid embryos in IVF.