A study on the hypoglycemic and hypolipidemic effects of an ayurvedic drug Rajanyamalakadi in diabetic patients |
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Authors: | P Faizal S Suresh R Satheesh Kumar K T Augusti |
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Institution: | (1) Department of Biochemistry, School of Health Sciences, Kannur University, Kannur, Kerala, India;(2) School of Medical Education, M.G.University, Kottayam, Kerala, India;(3) Hubei College of Chinese Traditional Medicine, Wuhan City, China;(4) Department of Biochemistry, School of Health Sciences, Kannur University, Thalassery Campus, P.O.Palayad, 670661 Kannur, Kerala, India |
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Abstract: | A study was undertaken for evaluating the hypoglycemic and hypolipidemic effects of an ayurvedic medicine “Rajanyamalakadi”
containing Curcuma longa, Emblica officinalis and Salacia oblonga in type II diabetic patients over a period of 3 months.
Ethical committee consent for the study was given by the Director, Indian Systems of Medicine, Kerala. A total of 43 patients
with established diabetes mellitus as adjudged from clinical features and FBS values, appeared for the camp (Age group 35–75
yrs). An informed consent for the study was obtained from each patient. The clinical proforma was given to each patient to
collect data such as height, weight, diet pattern, previous history of illness etc. The ongoing antidiabetic medications were
stopped under medical supervision and the patients were provided with ‘Rajanyamalakadi’ tablets (dose 1–2 tablets each weighing
500mg). The dosage of the drug was decided by the supervising medical officer on a case to case basis, taking note of the
clinical conditions and responsiveness of the patients. The patients were monitored for three months, who were divided into
6 groups based on their age and again into two groups, 5 & 6, based on their mean FBS values. ie; Normal Persons, Diabetics
of age groups 35–45yrs, 46–55yrs, >55yrs and those with FBS < 145.9 mg% and > 145.9 mg%. The Ayurvedic medicine “Rajanyamalakadi”
has showed significant antidiabetic, hypolipidemic and antioxidant effects. In addition to that significant ameliorating effects
on the elevated serum AST and ALT activities were also demonstrated by the treatment. The nutraceuticals present in the drug
like Terpenoids, Polyphenols, Curcumin etc are responsible for the medicinal effects. |
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Keywords: | Rajanyamalakadi Antidiabetic Hypoglycemic Hypolipidemic Salacia oblonga Curcuma longa Emblica officinalis |
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