Differential erythrocyte agglutination pattern in normal and cancer patients with Synadenium grantii root (Hook f) lectin |
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| Authors: | Pushpa P. Durgawale P. S. Shukla Shubhangi D. Sontakke P. G. Chougule |
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| Affiliation: | (1) Dept of Biochemistry, Krishna Institute of Medical Sciences, 415110 Karad;(2) Dept of Surgery, Krishna Institute of Medical Sciences, 415110 Karad;(3) Dept. of Biochemistry, Shivaji University, 416001 Kolhapur |
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| Abstract: | In the present study the property of lectin agglutination in blood on normal and different cancer patients has been observed. The purifiedSynadenium grantii root lectin was non blood group specific and its utility as a diagnostic tool in malignancy was studied. Hemagglutination (units/ml) of red blood cells of different types of cancer was compared with the normal control's red blood cells. Out of 113 total cancer patients, only a group of 29 breast cancer patients showed significant increase in titre value (P<0.05) compared to normal control. |
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| Keywords: | Lectin Red cell membrane Cancer Hemagglutination |
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