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Pulse-line intersection method with unboxed artificial intelligence for hesitant pulse wave classification
Institution:1. Department of Computer Science and Information Engineering, Asia University, Taichung, Taiwan;2. Department of Medical Research, China Medical University Hospital, China Medical University Taichung, Taiwan;3. Department of Information Technology, Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia;4. Department of Electrical Engineering, Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia;5. Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan;6. Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan;7. Chinese Medicine Research Center, China Medical University, Taichung, Taiwan;8. School of Post-Baccalaureate Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan;9. Department of Chinese Medicine, Asia University Hospital, Taichung, Taiwan;10. Department of Food Nutrition and Health Biotechnology, Taichung, Asia University, Taiwan;1. Business School, Shandong University of Technology, Zibo, 255000, China;2. Information Center, Jiangsu Academy of Agricultural Sciences, Nanjing, 210014;3. Centre for Science and Technology Studies (CWTS), Leiden University, Leiden 2300 AX, the Netherlands;4. Information Research Institute of Shandong Academy of Science, Jinan, 250014, China;5. School of Economics, Shandong University of Technology, Zibo, 255049, Shandong, China
Abstract:State-of-the-art artificial intelligence (AI) methods are progressively strengthened in Traditional Chinese Medicine (TCM) pulse palpation, aiding physicians to make comprehensive preliminary clinical decisions through non-invasive diagnostics. One of the well-known proven examinations i.e., hesitant pulse wave diagnosis, is a sign that the blood circulation of a person is sluggish. This examination provides a preliminary diagnosis for physiological problems. Modern AI methods such as artificial neural networks achieve better performance than traditional methods; however, the final decision of such examination lacks of interpretability. In clinical situations, patients need an easy-to-understand diagnosis to be provided for selecting appropriate clinical treatment. Therefore, this study presents feature extraction and clinical decision support systems based on Pulse-Line Intersection (PLI) and eXplainability AI (XAI) methods. The pulses were recorded from 46 patients in six different measurement points for six seconds. In addition, a comparison of several AI methods was provided to classify hesitant and normal pulse. The contribution of each feature in the classification process was analyzed by unboxing each predictive intelligence model. The results revealed that all models performed comparably, evaluated using performance matric on the testing data with average F1-score of Logistic Regression, Support Vector Machine, Random Forest, XGBoost, Multi-Layer Perceptron, and Long Short-Term Memory were 0.74, 0.74, 0.74, 0.78, 0.73, and 0.80, respectively. This work suggests that modern AI methods can provide more comprehensive explainability and higher accuracy than traditional method rankings.
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