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用乘子法同时测定复方替硝唑含漱液中二组分的含量
引用本文:魏得良,郭皖北,周明达,王曼娟,刘建华.用乘子法同时测定复方替硝唑含漱液中二组分的含量[J].衡阳师范学院学报,2006,27(6):47-50.
作者姓名:魏得良  郭皖北  周明达  王曼娟  刘建华
作者单位:1. 湘南学院,化学与生命科学系,湖南郴州,423000
2. 中南大学湘雅二医院,内分泌及代谢研究所,湖南长沙,410011
3. 中南大学,化学化工学院,湖南长沙,410078
基金项目:the educational depart ment of Hunan Province(05C630)
摘    要:用乘子法处理多波长吸光度数据,同时测定复方替硝唑含漱液中二组分的含量。简要介绍了乘子法的原理和计算步骤,模拟样品中醋酸氯已定、替硝唑的平均回收率分别为99.75%,100.17%,标准偏差分别为0.73%,0.42%(n=10),对三个批号实际样品的测定结果与标准方法吻合。与标准方法相比,该方法具有简便、快速、易于实现自动分析的优点。

关 键 词:乘子法  分光光度法  复方替硝唑含漱液  醋酸氯已定  替硝唑
文章编号:1673-0313(2006)06-0047-04
收稿时间:2006-07-13
修稿时间:2006年7月13日

Simultaneous Determination of two Components in Compound Tinidazole Gargles by Multiply Factor Method
WEI De-liang,GUO Wan-bei,ZHOU Ming-da,WANG Man-juan,LIU Jian-hua.Simultaneous Determination of two Components in Compound Tinidazole Gargles by Multiply Factor Method[J].journal of Hengyang Normal University,2006,27(6):47-50.
Authors:WEI De-liang  GUO Wan-bei  ZHOU Ming-da  WANG Man-juan  LIU Jian-hua
Institution:1. Department of Chemistry and Life Science, Xiangnan University, Chenzhou Hunan 423000, China2. Institute of Endocrinology and Metabolism, No. 2 Xiang-Ya Hospital Attached to Central South University, Changsha Hunan 410011, China 3. College of Chemistry and Chemical Engineering, Central South University, Changsha Hunan 410078, Chian
Abstract:In this paper, the basic principle and computing of multiply factor method applied to multicomponent analysis were discussed. The method was applied to simultaneous determination of two components in compound tinidazole gargles. The average recovery of Chlorhexidine and tinidazole in simulation samples was 99.75%、100.17% and relative standard deviations for them were 0.73%、0.42% respectively (n=10). The results of determination for three batches of actual samples were agreed with those by standard method. This method promises well to be adopted as an official assay method for compound tinidazole gargles.
Keywords:multiply factor method  spectrophotometry  compound tinidazole gargles  Chlorhexidine  Tinidazole
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