窄谱紫外线联合0.005%卡泊三醇治疗寻常性斑块状银屑病的疗效观察

目的评价窄谱紫外线联合0.05%卡泊三醇治疗寻常性斑块状银屑病的疗效和安全性。方法对35例轻、中度寻常性斑块状银屑病患者采用窄谱紫外线每周3次照射,联合0.005%卡泊三醇每天2次外用,共治疗8周,用PASI积分评价疗效。结果治疗开始2周后出现疗效,随着治疗时间的延长,有效率逐渐提高,治疗结束时痊愈率达到40%,有效率达85.71%,4例发生皮肤刺激反应,占11.43%。结论窄谱紫外线联合0.05%卡泊三醇治疗寻常性斑块状银屑病具有起效快、疗效好、副作用小的优点。

Curative Effect Observation of the Narrow Spectrum Ultraviolet with 0.005% Calcipotrial in the Treatment of Plaque Psoriasis Vulgaris

Objective:To evaluate the curative effect and safety of the narrow-band ultraviolet with 0.05% calcipotriol in the treatment of plaque psoriasis vulgaris.Methods:35 patients with the mild to moderate plaque psoriasis vulgaris were treated for 8 weeks with narrow-spectrum ultraviolet radiation three times a week,coupled with 0.005% calcipotriol twice daily topical,and assessed by the PASI evaluation points.Results:The curative effect of the treatment occurs two weeks later and increases over time.The treatment concludes with the cure rate of 40%,effective rate of 85.71%,and 4 cases of skin irritation accounting for 11.43%.Conclusion:Narrow-band ultraviolet 0.05% calcipotriol with plaque psoriasis vulgaris has the advantages of the rapid and satisfactory effect and little side effect.