Plasma antioxidant vitamins and lipid peroxidation products in pregnancy induced hypertension |
| |
Authors: | G M Rao P Sumita M Roshni M N Ashtagimatt |
| |
Institution: | (1) Department of Biochemistry, Center for Basic Sciences Kasturba Medical College Bejai, 575 004 Mangalore |
| |
Abstract: | It has been suggested that antioxidant systems are impaired in pregnancy induced hypertension and hence patients are exposed
to oxidative stress. In order to investigate the relationship between lipid peroxidation and certain antioxidant parameters
in blood of pregnancy induced hypertension (PIH) cases, 25 normotensive and 23 PIH samples were studied. In the present study,
thiobarbituric acid reactive substances showed a tendency to increase, however the increase remained statistically insignificant.
Plasma ascorbic acid level remained unaltered and Vitamin E showed a tendency to increase in the study group. The findings
implicate oxidative stress in the disease and cite the biochemical rationale for clinical trials of antioxidants to prevent
and treat pregnancy induced hypertension. |
| |
Keywords: | Vitamin C Vitamin E Lipid peroxidation PIH |
本文献已被 SpringerLink 等数据库收录! |