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Serum gamma glutamyl transferase (γ-GT) activity in alcoholics with liver abscess and chronic alcoholics |
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| Authors: | G Rajagopal K M Mohammed Rafi |
| Institution: | (1) Department of Biochemistry, Rajah Muthiah Medical College, Annamalai University, 608002 Annamalainagar, India;(2) Present address: B. P. Koirala Institute of Health Sciences, Dharan, Nepal;(3) Present address: Dudley Group of Hospitals, NHS Trust, Dudley, UK;(4) 134, 2nd Main Road, Viduthalai Nagar. S. Kolathur, 600117 Chennai |
| Abstract: | Gamma Glutamyl Transferase (γ-GT) is a microsomal enzyme. Its activity in serum is assayed in alcoholics with liver abscess and alcoholics without liver abscess after screening by ultrasonography. The enzyme activity in serum is increased by 334% in the patients with liver abscess compared to normal control subjects (p<0.0001), and 172% when compared to patients with chronic alcoholism without liver abscess (p<0.0001). The enzyme activity was increased by 59.3% in the serum of patients without liver abscess compared to the normal control subjects (p<0.001). Measurement of γ-GT in serum appears to be a sensitive index in the diagnosis of alcoholics with liver abscess. |
| Keywords: | Alcoholic liver abscess γ -GT in chronic alcoholics serum γ -GT |
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