| N~1,N~5-二(1-甲基咪唑-2-酰基)二乙基三胺的合成与表征 |
| |
| 引用本文： | 周成勇,张宝秀. N~1,N~5-二(1-甲基咪唑-2-酰基)二乙基三胺的合成与表征[J]. 长治学院学报, 2011, 28(2): 1-4 |
| |
| 作者姓名： | 周成勇 张宝秀 |
| |
| 作者单位： | 长治学院化学系,山西长治,046011 |
| |
| 基金项目： | 山西省高校科技开发项目资助课题(№:2007154) |
| |
| 摘 要： | 文章首次报道了一种含咪唑环多胺类化合物N1,N5-二(1-甲基咪唑-2-酰基)二乙基三胺的合成方法,以此化合物为基础,可以合成对称平行的发卡式多酰胺分子,以期对DNA序列进行新的特异性识别,从而开发研制新型有效的工具酶或抗癌药物。合成方法简便易行、耗时短、不需要过柱分离,每一步合成都有较高的产率。
|
| 关 键 词： | 咪唑 二乙基三胺 多胺 化学核酸酶 |
Synthesis and Characterization of N~1,N~5-Bis(1-methylimidazole-2-carbonyl)Diethylenetriamine |
| |
| ZHOU Cheng-Yong,ZHANG Bao-xiu. Synthesis and Characterization of N~1,N~5-Bis(1-methylimidazole-2-carbonyl)Diethylenetriamine[J]. Journal of Changzhi University, 2011, 28(2): 1-4 |
| |
| Authors: | ZHOU Cheng-Yong ZHANG Bao-xiu |
| |
| Affiliation: | ZHOU Cheng-Yong,ZHANG Bao-xiu(Department of Chemistry,Changzhi University,Changzhi Shanxi 046011) |
| |
| Abstract: | In this paper,the synthesis of a sort of symmetrical and parallel polyamide,N1,N5-Bis(1-methylimidazole-2-carbonyl)diethylenetriamine,was reported first.The whole process was also simple and convenient without column chromatography with high yields.The target compound was anticipated to recognize DNA sequence specifically and cleave it at predetermined site. |
| |
| Keywords: | imidazole diethylenetriamine polyamide chemical nuclease |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
