细胞功能的可视化及信息整合分析——第69次“双清论坛”综述

20世纪生物学家由体外获得的大量生物分子和细胞的功能信息,亟待通过活体内动态研究加以证实。近年来迅速发展的分子成像技术使得细胞功能的可视化与信息整合研究成为可能。国家自然科学基金委员会于2011年9月16—18日,在北京召开了主题为"细胞功能的可视化及信息整合分析"的第69期"双清论坛"学术研讨会。论坛围绕生理与病理状态宿主细胞功能的动态定量可视化及相关信息学研究的现状、前沿热点问题、发展趋势以及相关新技术新仪器的研发等多方面展开研讨。同时,结合我国的研究现状,分析我国在该领域的研究基础与优势,凝练和提出我国在这方面急需关注和解决的重要基础科学问题,以及今后5—10年的重点资助方向。来自国内外12所高校和科研院所的免疫学、信息学、医学、纳米科学和化学等领域的专家、学者出席此次论坛。

REVIEW OF THE 69TH SHUANGQING FORUM ON "VISUALIZATION OF CELL FUNCTION AND INFORMATION INTEGRATION ANALYSIS"

During the 20th century,biologists have gained significant insights into the function of biological molecules and cells through the design and execution of ex vivo experiments.To further expand and build on this knowledge,there is an urgent need to explore dynamic in vivo studies.In recent years,the rapid development of molecular imaging technologies has enabled scientists to further investigate,with ever increasing detail in the visualization of cellular functional events,and the integration of these data with the existing information.To advance this process,the 69th Shuangqing forum was held in Beijing during 16—18 September 2011 by the National Natural Science Foundation of China with a focus on the "Visualization of cell function and information integration analysis".This conference discussed the dynamic quantitative visualization of the function of host cells under physiological and disease states and related informatics studies. Cutting-edge issues,trends in R & D,as well as the development of new technologies and instruments were also discussed.Moreover,in view of the current research status in China,a summary of the research foundation and advantages of the field was made.Significant efforts were devoted to the important basic scientific issues requiring urgent attention as well as the proposal for resolutions and major funding directions in the next 5—10 years.Scholars with various backgrounds,including the field of immunology,informatics, medicine,nanoscience and chemistry,from the 12 universities and research institutes both domestic and abroad attended this forum.