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Controlling droplet incubation using close-packed plug flow
Authors:Mary Pascaline  Abate Adam R  Agresti Jeremy J  Weitz David A
Affiliation:1Department of Physics/School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02139, USA;2Department of Biology, Amyris, 5885 Hollis Street, Suite 100, Emeryville, California 94608, USA
Abstract:Controlling droplet incubation is critical for droplet-based microfluidic applications; however, current techniques are either of limited precision or place strict limits on the incubation times that can be achieved. Here, we present a simple technique to control incubation time by exploiting close-packed plug flow. In contrast to other techniques, this technique is applicable to very short and very long incubation times.
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