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Deep lingual arterial chemoembolization of tongue carcinoma with microcapsuled anticancer drug
Authors:He Hong  Huang Jian-qi  Ping Fei-yun  Chen Guan-fu  Zhang Su-zhan
Affiliation:(1) Department of Stomatology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310009, China;(2) Cancer Institute, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310009, China
Abstract:Objective: Microcapsule chemoembolism is a promising treatment of tumors. We describe a deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum. Methods: Lingual artery cast specimens from cadavers were microscopically examined, and 78 patients with tongue cancer were recruited and treated with the deep lingual arterial embolization therapy. Results: Microcapsule embolism occurred approximately at the fifth or sixth level of the deep lingual artery branches. The five-year survival rate was 88.5% (69 out of 78), and the ten-year survival rate 52.6% (41 out of 78). Conclusion: The deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum is an effective therapy to treat carcinoma in mid-margin or mid-body of the tongue.
Keywords:Tongue carcinoma  Artery cast  Arterial chemoembolization  Deep lingual arterial embolization  Anticancer drug  Carboplatinum
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