| Dependence of the E. coli promoter strength and physical parameters upon the nucleotide sequence |
| |
| 作者姓名： | BEREZHNOY AndreyY. SHCKORBATOV Yuriy G. |
| |
| 作者单位： | National Scientific Center，Kharkov Physical-Technical Institute，Kharkov 61108，Ukraine，Institute of Biology，Kharkov National University，Kharkov 61077，Ukraine |
| |
| 摘 要： |
|
Dependence of the E.coli promoter strength and physical parameters upon the nucleotide sequence |
| |
| BEREZHNOY AndreyY.,SHCKORBATOV Yuriy G..Dependence of the E. coli promoter strength and physical parameters upon the nucleotide sequence[J].Journal of Zhejiang University Science,2005,6(11). |
| |
| Authors: | BEREZHNOY Andrey Y SHCKORBATOV Yuriy G |
| |
| Abstract: | The energy of interaction between complementary nucleotides in promoter sequences ofE. coli was calculated and visualized. The graphic method for presentation of energy properties of promoter sequences was elaborated on. Data obtained indicated that energy distribution through the length of promoter sequence results in picture with minima at -35, -8 and 7 regions corresponding to areas with elevated AT (adenine-thymine) content. The most important difference from the random sequences area is related to -8. Four promoter groups and their energy properties were revealed. The promoters with minimal and maximal energy of interaction between complementary nucleotides have low strengths, the strongest promoters correspond to promoter clusters characterized by intermediate energy values. |
| |
| Keywords: | DNA sequence Promoter strength Nucleotide pair energy -35 sequence -10 sequence 7 sequence 2005 B1063 Document code: A Key words: DNA sequence Promoter strength Nucleotide pair energy -35 sequence -10 sequence 7 sequence |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
